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EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair.
Koyen AE, Madden MZ, Park D, Minten EV, Kapoor-Vazirani P, Werner E, Pfister NT, Haji-Seyed-Javadi R, Zhang H, Xu J, Deng N, Duong DM, Pecen TJ, Frazier Z, Nagel ZD, Lazaro JB, Mouw KW, Seyfried NT, Moreno CS, Owonikoko TK, Deng X, Yu DS. Koyen AE, et al. Among authors: park d. Oncogene. 2020 Jun;39(25):4798-4813. doi: 10.1038/s41388-020-1332-2. Epub 2020 May 26. Oncogene. 2020. PMID: 32457468 Free PMC article.
Novel small-molecule inhibitors of Bcl-XL to treat lung cancer.
Park D, Magis AT, Li R, Owonikoko TK, Sica GL, Sun SY, Ramalingam SS, Khuri FR, Curran WJ, Deng X. Park D, et al. Cancer Res. 2013 Sep 1;73(17):5485-96. doi: 10.1158/0008-5472.CAN-12-2272. Epub 2013 Jul 3. Cancer Res. 2013. PMID: 23824742 Free PMC article.
Small-molecule Bax agonists for cancer therapy.
Xin M, Li R, Xie M, Park D, Owonikoko TK, Sica GL, Corsino PE, Zhou J, Ding C, White MA, Magis AT, Ramalingam SS, Curran WJ, Khuri FR, Deng X. Xin M, et al. Among authors: park d. Nat Commun. 2014 Sep 17;5:4935. doi: 10.1038/ncomms5935. Nat Commun. 2014. PMID: 25230299 Free PMC article.
Small-Molecule Bcl2 BH4 Antagonist for Lung Cancer Therapy.
Han B, Park D, Li R, Xie M, Owonikoko TK, Zhang G, Sica GL, Ding C, Zhou J, Magis AT, Chen ZG, Shin DM, Ramalingam SS, Khuri FR, Curran WJ, Deng X. Han B, et al. Among authors: park d. Cancer Cell. 2015 Jun 8;27(6):852-63. doi: 10.1016/j.ccell.2015.04.010. Epub 2015 May 21. Cancer Cell. 2015. PMID: 26004684 Free PMC article.
Targeting DNA Replication Stress for Cancer Therapy.
Zhang J, Dai Q, Park D, Deng X. Zhang J, et al. Among authors: park d. Genes (Basel). 2016 Aug 19;7(8):51. doi: 10.3390/genes7080051. Genes (Basel). 2016. PMID: 27548226 Free PMC article. Review.
9,935 results