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EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair.
Koyen AE, Madden MZ, Park D, Minten EV, Kapoor-Vazirani P, Werner E, Pfister NT, Haji-Seyed-Javadi R, Zhang H, Xu J, Deng N, Duong DM, Pecen TJ, Frazier Z, Nagel ZD, Lazaro JB, Mouw KW, Seyfried NT, Moreno CS, Owonikoko TK, Deng X, Yu DS. Koyen AE, et al. Among authors: moreno cs. Oncogene. 2020 Jun;39(25):4798-4813. doi: 10.1038/s41388-020-1332-2. Epub 2020 May 26. Oncogene. 2020. PMID: 32457468 Free PMC article.
Loss of HOXC6 expression induces apoptosis in prostate cancer cells.
Ramachandran S, Liu P, Young AN, Yin-Goen Q, Lim SD, Laycock N, Amin MB, Carney JK, Marshall FF, Petros JA, Moreno CS. Ramachandran S, et al. Among authors: moreno cs. Oncogene. 2005 Jan 6;24(1):188-98. doi: 10.1038/sj.onc.1207906. Oncogene. 2005. PMID: 15637592
An expanded universe of cancer targets.
Hahn WC, Bader JS, Braun TP, Califano A, Clemons PA, Druker BJ, Ewald AJ, Fu H, Jagu S, Kemp CJ, Kim W, Kuo CJ, McManus M, B Mills G, Mo X, Sahni N, Schreiber SL, Talamas JA, Tamayo P, Tyner JW, Wagner BK, Weiss WA, Gerhard DS; Cancer Target Discovery and Development Network. Hahn WC, et al. Cell. 2021 Mar 4;184(5):1142-1155. doi: 10.1016/j.cell.2021.02.020. Cell. 2021. PMID: 33667368 Free PMC article. Review.
Systematic discovery of mutation-directed neo-protein-protein interactions in cancer.
Mo X, Niu Q, Ivanov AA, Tsang YH, Tang C, Shu C, Li Q, Qian K, Wahafu A, Doyle SP, Cicka D, Yang X, Fan D, Reyna MA, Cooper LAD, Moreno CS, Zhou W, Owonikoko TK, Lonial S, Khuri FR, Du Y, Ramalingam SS, Mills GB, Fu H. Mo X, et al. Among authors: moreno cs. Cell. 2022 May 26;185(11):1974-1985.e12. doi: 10.1016/j.cell.2022.04.014. Epub 2022 May 4. Cell. 2022. PMID: 35512704 Free PMC article.
Identification of a novel small molecule HIF-1alpha translation inhibitor.
Narita T, Yin S, Gelin CF, Moreno CS, Yepes M, Nicolaou KC, Van Meir EG. Narita T, et al. Among authors: moreno cs. Clin Cancer Res. 2009 Oct 1;15(19):6128-36. doi: 10.1158/1078-0432.CCR-08-3180. Epub 2009 Sep 29. Clin Cancer Res. 2009. PMID: 19789328 Free PMC article.
117 results