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Impaired leucocyte activation is underlining the lower thrombotic risk of essential thrombocythaemia patients with CALR mutations as compared with those with the JAK2 mutation.
Torregrosa JM, Ferrer-Marín F, Lozano ML, Moreno MJ, Martinez C, Anton AI, Rivera J, Vicente V. Torregrosa JM, et al. Among authors: rivera j. Br J Haematol. 2016 Mar;172(5):813-5. doi: 10.1111/bjh.13539. Epub 2015 Jun 30. Br J Haematol. 2016. PMID: 26132594 Free article. No abstract available.
Novel mutations in RASGRP2, which encodes CalDAG-GEFI, abrogate Rap1 activation, causing platelet dysfunction.
Lozano ML, Cook A, Bastida JM, Paul DS, Iruin G, Cid AR, Adan-Pedroso R, Ramón González-Porras J, Hernández-Rivas JM, Fletcher SJ, Johnson B, Morgan N, Ferrer-Marin F, Vicente V, Sondek J, Watson SP, Bergmeier W, Rivera J. Lozano ML, et al. Among authors: rivera j. Blood. 2016 Sep 1;128(9):1282-9. doi: 10.1182/blood-2015-11-683102. Epub 2016 May 27. Blood. 2016. PMID: 27235135 Free PMC article. Clinical Trial.
Quality assessment and transfusion efficacy of buffy coat-derived platelet concentrates washed with platelet additive solution.
Fernández-Muñoz H, Castilla-Llorente C, Plaza EM, Martínez-Millán C, Heras I, Iniesta P, Amigo ML, Ferrer-Marin F, Candela MJ, Lozano ML, Vicente V, Rivera J. Fernández-Muñoz H, et al. Among authors: rivera j. Blood Transfus. 2018 May;16(3):273-278. doi: 10.2450/2017.0277-16. Epub 2017 Apr 13. Blood Transfus. 2018. PMID: 28488971 Free PMC article. Clinical Trial.
Identification of two novel mutations in RASGRP2 affecting platelet CalDAG-GEFI expression and function in patients with bleeding diathesis.
Sevivas T, Bastida JM, Paul DS, Caparros E, Palma-Barqueros V, Coucelo M, Marques D, Ferrer-Marín F, González-Porras JR, Vicente V, Hernández-Rivas JM, Watson SP, Lozano ML, Bergmeier W, Rivera J. Sevivas T, et al. Among authors: rivera j. Platelets. 2018 Mar;29(2):192-195. doi: 10.1080/09537104.2017.1336214. Epub 2017 Aug 1. Platelets. 2018. PMID: 28762304 Free PMC article.
Comprehensive comparison of neonate and adult human platelet transcriptomes.
Caparrós-Pérez E, Teruel-Montoya R, López-Andreo MJ, Llanos MC, Rivera J, Palma-Barqueros V, Blanco JE, Vicente V, Martínez C, Ferrer-Marín F. Caparrós-Pérez E, et al. Among authors: rivera j. PLoS One. 2017 Aug 16;12(8):e0183042. doi: 10.1371/journal.pone.0183042. eCollection 2017. PLoS One. 2017. PMID: 28813466 Free PMC article.
Down Regulation of the Munc18b-syntaxin-11 Complex and β1-tubulin Impairs Secretion and Spreading in Neonatal Platelets.
Caparrós-Pérez E, Teruel-Montoya R, Palma-Barquero V, Torregrosa JM, Blanco JE, Delgado JL, Lozano ML, Vicente V, Sola-Visner M, Rivera J, Martínez C, Ferrer-Marín F. Caparrós-Pérez E, et al. Among authors: rivera j. Thromb Haemost. 2017 Nov;117(11):2079-2091. doi: 10.1160/TH17-04-0241. Epub 2017 Nov 30. Thromb Haemost. 2017. PMID: 29044293
2,232 results