Zhang Y - Search Results

1

Synthesis and biological evaluation of 4-(pyridin-4-oxy)-3-(3,3-difluorocyclobutyl)-pyrazole derivatives as novel potent transforming growth factor-β type 1 receptor inhibitors.

Xu G, Zhang Y, Wang H, Guo Z, Wang X, Li X, Chang S, Sun T, Yu Z, Xu T, Zhao L, Wang Y, Yu W. Xu G, et al. Among authors: zhang y. Eur J Med Chem. 2020 Jul 15;198:112354. doi: 10.1016/j.ejmech.2020.112354. Epub 2020 Apr 29. Eur J Med Chem. 2020. PMID: 32387837

2

Synthesis and identification of [1,3,5]triazine-pyridine biheteroaryl as a novel series of potent cyclin-dependent kinase inhibitors.

Kuo GH, Deangelis A, Emanuel S, Wang A, Zhang Y, Connolly PJ, Chen X, Gruninger RH, Rugg C, Fuentes-Pesquera A, Middleton SA, Jolliffe L, Murray WV. Kuo GH, et al. Among authors: zhang y. J Med Chem. 2005 Jul 14;48(14):4535-46. doi: 10.1021/jm040214h. J Med Chem. 2005. PMID: 15999992

3

Synthesis and structure-activity relationships of pyrazine-pyridine biheteroaryls as novel, potent, and selective vascular endothelial growth factor receptor-2 inhibitors.

Kuo GH, Prouty C, Wang A, Emanuel S, Deangelis A, Zhang Y, Song F, Beall L, Connolly PJ, Karnachi P, Chen X, Gruninger RH, Sechler J, Fuentes-Pesquera A, Middleton SA, Jolliffe L, Murray WV. Kuo GH, et al. Among authors: zhang y. J Med Chem. 2005 Jul 28;48(15):4892-909. doi: 10.1021/jm058205b. J Med Chem. 2005. PMID: 16033269

4

Discovery and optimization of 3-(2-(Pyrazolo[1,5-a]pyrimidin-6-yl)ethynyl)benzamides as novel selective and orally bioavailable discoidin domain receptor 1 (DDR1) inhibitors.

Gao M, Duan L, Luo J, Zhang L, Lu X, Zhang Y, Zhang Z, Tu Z, Xu Y, Ren X, Ding K. Gao M, et al. Among authors: zhang l, zhang z, zhang y. J Med Chem. 2013 Apr 25;56(8):3281-95. doi: 10.1021/jm301824k. Epub 2013 Apr 10. J Med Chem. 2013. PMID: 23521020

5

Natural products as sources of new fungicides (III): Antifungal activity of 2,4-dihydroxy-5-methylacetophenone derivatives.

Shi W, Dan WJ, Tang JJ, Zhang Y, Nandinsuren T, Zhang AL, Gao JM. Shi W, et al. Among authors: zhang al, zhang y. Bioorg Med Chem Lett. 2016 May 1;26(9):2156-8. doi: 10.1016/j.bmcl.2016.03.073. Epub 2016 Mar 18. Bioorg Med Chem Lett. 2016. PMID: 27025344

6

A new Prenylated Flavonoid induces G0/G1 arrest and apoptosis through p38/JNK MAPK pathways in Human Hepatocellular Carcinoma cells.

Wang D, Sun Q, Wu J, Wang W, Yao G, Li T, Li X, Li L, Zhang Y, Cui W, Song S. Wang D, et al. Among authors: zhang y. Sci Rep. 2017 Jul 18;7(1):5736. doi: 10.1038/s41598-017-05955-0. Sci Rep. 2017. PMID: 28720813 Free PMC article.

7

Design, synthesis and biological evaluation of novel 4-aminoquinazolines as dual target inhibitors of EGFR-PI3Kα.

Ding HW, Deng CL, Li DD, Liu DD, Chai SM, Wang W, Zhang Y, Chen K, Li X, Wang J, Song SJ, Song HR. Ding HW, et al. Among authors: zhang y. Eur J Med Chem. 2018 Feb 25;146:460-470. doi: 10.1016/j.ejmech.2018.01.081. Epub 2018 Jan 31. Eur J Med Chem. 2018. PMID: 29407971

8

Discovery of Novel Schizocommunin Derivatives as Telomeric G-Quadruplex Ligands That Trigger Telomere Dysfunction and the Deoxyribonucleic Acid (DNA) Damage Response.

Che T, Chen SB, Tu JL, Wang B, Wang YQ, Zhang Y, Wang J, Wang ZQ, Zhang ZP, Ou TM, Zhao Y, Tan JH, Huang ZS. Che T, et al. Among authors: zhang zp, zhang y. J Med Chem. 2018 Apr 26;61(8):3436-3453. doi: 10.1021/acs.jmedchem.7b01615. Epub 2018 Apr 11. J Med Chem. 2018. PMID: 29618208

9

Novel sarsasapogenin-triazolyl hybrids as potential anti-Alzheimer's agents: Design, synthesis and biological evaluation.

Wang W, Wang W, Yao G, Ren Q, Wang D, Wang Z, Liu P, Gao P, Zhang Y, Wang S, Song S. Wang W, et al. Among authors: zhang y. Eur J Med Chem. 2018 May 10;151:351-362. doi: 10.1016/j.ejmech.2018.03.082. Epub 2018 Apr 3. Eur J Med Chem. 2018. PMID: 29635167

10

Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer.

Xue X, Zhang Y, Wang C, Zhang M, Xiang Q, Wang J, Wang A, Li C, Zhang C, Zou L, Wang R, Wu S, Lu Y, Chen H, Ding K, Li G, Xu Y. Xue X, et al. Among authors: zhang m, zhang c, zhang y. Eur J Med Chem. 2018 May 25;152:542-559. doi: 10.1016/j.ejmech.2018.04.034. Epub 2018 Apr 21. Eur J Med Chem. 2018. PMID: 29758518

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