Wang X - Search Results

1

Synthesis and biological evaluation of 4-(pyridin-4-oxy)-3-(3,3-difluorocyclobutyl)-pyrazole derivatives as novel potent transforming growth factor-β type 1 receptor inhibitors.

Xu G, Zhang Y, Wang H, Guo Z, Wang X, Li X, Chang S, Sun T, Yu Z, Xu T, Zhao L, Wang Y, Yu W. Xu G, et al. Among authors: wang h, wang x, wang y. Eur J Med Chem. 2020 Jul 15;198:112354. doi: 10.1016/j.ejmech.2020.112354. Epub 2020 Apr 29. Eur J Med Chem. 2020. PMID: 32387837

2

Novel 8-deaza-5,6,7,8-tetrahydroaminopterin derivatives as dihydrofolate inhibitor: design, synthesis and antifolate activity.

Zhang Z, Wu J, Ran F, Guo Y, Tian R, Zhou S, Wang X, Liu Z, Zhang L, Cui J, Liu J. Zhang Z, et al. Among authors: wang x. Eur J Med Chem. 2009 Feb;44(2):764-71. doi: 10.1016/j.ejmech.2008.04.017. Epub 2008 May 4. Eur J Med Chem. 2009. PMID: 18555562

3

Synthesis and biological evaluation of novel 2-arylalkylthio-4-amino-6-benzyl pyrimidines as potent HIV-1 non-nucleoside reverse transcriptase inhibitors.

Qin H, Liu C, Zhang J, Guo Y, Zhang S, Zhang Z, Wang X, Zhang L, Liu J. Qin H, et al. Among authors: wang x. Bioorg Med Chem Lett. 2010 May 1;20(9):3003-5. doi: 10.1016/j.bmcl.2009.04.051. Epub 2009 Apr 18. Bioorg Med Chem Lett. 2010. PMID: 20347295

4

Design, synthesis, and biological evaluation of 1-[(2-benzyloxyl/alkoxyl)methyl]-5-halo-6-aryluracils as potent HIV-1 non-nucleoside reverse transcriptase inhibitors with an improved drug resistance profile.

Wang X, Zhang J, Huang Y, Wang R, Zhang L, Qiao K, Li L, Liu C, Ouyang Y, Xu W, Zhang Z, Zhang L, Shao Y, Jiang S, Ma L, Liu J. Wang X, et al. Among authors: wang r. J Med Chem. 2012 Mar 8;55(5):2242-50. doi: 10.1021/jm201506e. Epub 2012 Feb 17. J Med Chem. 2012. PMID: 22283377 Free PMC article.

5

Mechanism-based design, synthesis and biological studies of N⁵-substituted tetrahydrofolate analogs as inhibitors of cobalamin-dependent methionine synthase and potential anticancer agents.

Zhang Z, Tian C, Zhou S, Wang W, Guo Y, Xia J, Liu Z, Wang B, Wang X, Golding BT, Griff RJ, Du Y, Liu J. Zhang Z, et al. Among authors: wang x, wang w, wang b. Eur J Med Chem. 2012 Dec;58:228-36. doi: 10.1016/j.ejmech.2012.09.027. Epub 2012 Oct 9. Eur J Med Chem. 2012. PMID: 23124219

6

Novel pyridinone derivatives as non-nucleoside reverse transcriptase inhibitors (NNRTIs) with high potency against NNRTI-resistant HIV-1 strains.

Li A, Ouyang Y, Wang Z, Cao Y, Liu X, Ran L, Li C, Li L, Zhang L, Qiao K, Xu W, Huang Y, Zhang Z, Tian C, Liu Z, Jiang S, Shao Y, Du Y, Ma L, Wang X, Liu J. Li A, et al. Among authors: wang x, wang z. J Med Chem. 2013 May 9;56(9):3593-608. doi: 10.1021/jm400102x. Epub 2013 Apr 19. J Med Chem. 2013. PMID: 23540737

7

Design, synthesis, and biological evaluation of (e)-3,4-dihydroxystyryl aralkyl sulfones and sulfoxides as novel multifunctional neuroprotective agents.

Ning X, Guo Y, Wang X, Ma X, Tian C, Shi X, Zhu R, Cheng C, Du Y, Ma Z, Zhang Z, Liu J. Ning X, et al. Among authors: wang x. J Med Chem. 2014 May 22;57(10):4302-12. doi: 10.1021/jm500258v. Epub 2014 May 6. J Med Chem. 2014. PMID: 24697335

8

Synthesis and biological evaluation of pyridinone analogues as novel potent HIV-1 NNRTIs.

Cao Y, Zhang Y, Wu S, Yang Q, Sun X, Zhao J, Pei F, Guo Y, Tian C, Zhang Z, Wang H, Ma L, Liu J, Wang X. Cao Y, et al. Among authors: wang h, wang x. Bioorg Med Chem. 2015 Jan 1;23(1):149-59. doi: 10.1016/j.bmc.2014.11.012. Epub 2014 Nov 14. Bioorg Med Chem. 2015. PMID: 25468035

9

Study on 2-arylthio-5-iodo pyrimidine derivatives as novel nonnucleoside inhibitors against hepatitis B virus DNA replication.

Zhao J, Tu J, Fan N, Chen X, Lu F, Zhang Y, Zhang L, Tian C, Zhang Z, Liu J, Wang X. Zhao J, et al. Among authors: wang x. Future Med Chem. 2016 May;8(7):751-63. doi: 10.4155/fmc.16.13. Epub 2016 May 13. Future Med Chem. 2016. PMID: 27172826

10

Design, synthesis and biological evaluation of (E)-3,4-dihydroxystyryl 4-acylaminophenethyl sulfone, sulfoxide derivatives as dual inhibitors of HIV-1 CCR5 and integrase.

Sun Y, Xu W, Fan N, Sun X, Ning X, Ma L, Liu J, Wang X. Sun Y, et al. Among authors: wang x. Bioorg Med Chem. 2017 Feb 1;25(3):1076-1084. doi: 10.1016/j.bmc.2016.12.035. Epub 2016 Dec 24. Bioorg Med Chem. 2017. PMID: 28082070

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