Denk H - Search Results

1

Liver Phenotypes of European Adults Heterozygous or Homozygous for Pi∗Z Variant of AAT (Pi∗MZ vs Pi∗ZZ genotype) and Noncarriers.

Schneider CV, Hamesch K, Gross A, Mandorfer M, Moeller LS, Pereira V, Pons M, Kuca P, Reichert MC, Benini F, Burbaum B, Voss J, Gutberlet M, Woditsch V, Lindhauer C, Fromme M, Kümpers J, Bewersdorf L, Schaefer B, Eslam M, Bals R, Janciauskiene S, Carvão J, Neureiter D, Zhou B, Wöran K, Bantel H, Geier A, Dirrichs T, Stickel F, Teumer A, Verbeek J, Nevens F, Govaere O, Krawczyk M, Roskams T, Haybaeck J, Lurje G, Chorostowska-Wynimko J, Genesca J, Reiberger T, Lammert F, Krag A, George J, Anstee QM, Trauner M, Datz C, Gaisa NT, Denk H, Trautwein C, Aigner E, Strnad P; European Alpha-1 Liver Study Group. Schneider CV, et al. Among authors: denk h. Gastroenterology. 2020 Aug;159(2):534-548.e11. doi: 10.1053/j.gastro.2020.04.058. Epub 2020 May 4. Gastroenterology. 2020. PMID: 32376409

2

Assessment of liver phenotype in adults with severe alpha-1 antitrypsin deficiency (Pi*ZZ genotype).

Kümpers J, Fromme M, Schneider CV, Trautwein C, Denk H, Hamesch K, Strnad P. Kümpers J, et al. Among authors: denk h. J Hepatol. 2019 Dec;71(6):1272-1274. doi: 10.1016/j.jhep.2019.08.011. Epub 2019 Oct 5. J Hepatol. 2019. PMID: 31594657 No abstract available.

3

Broad spectrum of hepatocyte inclusions in humans, animals, and experimental models.

Strnad P, Nuraldeen R, Guldiken N, Hartmann D, Mahajan V, Denk H, Haybaeck J. Strnad P, et al. Among authors: denk h. Compr Physiol. 2013 Oct;3(4):1393-436. doi: 10.1002/cphy.c120032. Compr Physiol. 2013. PMID: 24265234 Review.

4

Ursodeoxycholic acid aggravates bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles.

Fickert P, Zollner G, Fuchsbichler A, Stumptner C, Weiglein AH, Lammert F, Marschall HU, Tsybrovskyy O, Zatloukal K, Denk H, Trauner M. Fickert P, et al. Among authors: denk h. Gastroenterology. 2002 Oct;123(4):1238-51. doi: 10.1053/gast.2002.35948. Gastroenterology. 2002. PMID: 12360485

5

Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.

Fickert P, Fuchsbichler A, Wagner M, Zollner G, Kaser A, Tilg H, Krause R, Lammert F, Langner C, Zatloukal K, Marschall HU, Denk H, Trauner M. Fickert P, et al. Among authors: denk h. Gastroenterology. 2004 Jul;127(1):261-74. doi: 10.1053/j.gastro.2004.04.009. Gastroenterology. 2004. PMID: 15236191

6

From the origin of NASH to the future of metabolic fatty liver disease.

Geier A, Tiniakos D, Denk H, Trauner M. Geier A, et al. Among authors: denk h. Gut. 2021 Feb 25;70(8):1570-9. doi: 10.1136/gutjnl-2020-323202. Online ahead of print. Gut. 2021. PMID: 33632710 Free PMC article. Review.

7

High-fat diet triggers Mallory-Denk body formation through misfolding and crosslinking of excess keratin 8.

Kucukoglu O, Guldiken N, Chen Y, Usachov V, El-Heliebi A, Haybaeck J, Denk H, Trautwein C, Strnad P. Kucukoglu O, et al. Among authors: denk h. Hepatology. 2014 Jul;60(1):169-78. doi: 10.1002/hep.27068. Epub 2014 May 27. Hepatology. 2014. PMID: 24519272

8

24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.

Fickert P, Wagner M, Marschall HU, Fuchsbichler A, Zollner G, Tsybrovskyy O, Zatloukal K, Liu J, Waalkes MP, Cover C, Denk H, Hofmann AF, Jaeschke H, Trauner M. Fickert P, et al. Among authors: denk h. Gastroenterology. 2006 Feb;130(2):465-81. doi: 10.1053/j.gastro.2005.10.018. Gastroenterology. 2006. PMID: 16472600

9

Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice.

Wagner M, Fickert P, Zollner G, Fuchsbichler A, Silbert D, Tsybrovskyy O, Zatloukal K, Guo GL, Schuetz JD, Gonzalez FJ, Marschall HU, Denk H, Trauner M. Wagner M, et al. Among authors: denk h. Gastroenterology. 2003 Sep;125(3):825-38. doi: 10.1016/s0016-5085(03)01068-0. Gastroenterology. 2003. PMID: 12949728

10

Cross β-sheet conformation of keratin 8 is a specific feature of Mallory-Denk bodies compared with other hepatocyte inclusions.

Mahajan V, Klingstedt T, Simon R, Nilsson KP, Thueringer A, Kashofer K, Haybaeck J, Denk H, Abuja PM, Zatloukal K. Mahajan V, et al. Among authors: denk h. Gastroenterology. 2011 Sep;141(3):1080-1090.e1-7. doi: 10.1053/j.gastro.2011.05.039. Epub 2011 May 27. Gastroenterology. 2011. PMID: 21699779

BACKGROUND & AIMS: Mallory-Denk bodies (MDBs) are cytoplasmic protein aggregates in hepatocytes in steatohepatitis and other liver diseases. We investigated the molecular structure of keratin 8 (K8) and 18 (K18), sequestosome 1/p62, and ubiquitin, which are the major c …

BACKGROUND & AIMS: Mallory-Denk bodies (MDBs) are cytoplasmic protein aggregates in hepatocytes in steatohepatitis and other live …

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