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Aberrant non-canonical NF-κB signalling reprograms the epigenome landscape to drive oncogenic transcriptomes in multiple myeloma.
Nat Commun. 2024 Mar 21;15(1):2513. doi: 10.1038/s41467-024-46728-4.
Nat Commun. 2024.
PMID: 38514625
Free PMC article.
Towards a better preclinical cancer model - human immune aging in humanized mice.
Tan JHL, Hwang YY, Chin HX, Liu M, Tan SY, Chen Q.
Tan JHL, et al.
Immun Ageing. 2023 Sep 27;20(1):49. doi: 10.1186/s12979-023-00374-4.
Immun Ageing. 2023.
PMID: 37752597
Free PMC article.
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Cell Granularity Reflects Immune Cell Function and Enables Selection of Lymphocytes with Superior Attributes for Immunotherapy.
Wu T, Tan JHL, Sin WX, Luah YH, Tan SY, Goh M, Birnbaum ME, Chen Q, Cheow LF.
Wu T, et al. Among authors: tan jhl.
Adv Sci (Weinh). 2023 Oct;10(28):e2302175. doi: 10.1002/advs.202302175. Epub 2023 Aug 6.
Adv Sci (Weinh). 2023.
PMID: 37544893
Free PMC article.
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CD4+ T Cells Mediate the Development of Liver Fibrosis in High Fat Diet-Induced NAFLD in Humanized Mice.
Her Z, Tan JHL, Lim YS, Tan SY, Chan XY, Tan WWS, Liu M, Yong KSM, Lai F, Ceccarello E, Zheng Z, Fan Y, Chang KTE, Sun L, Chang SC, Chin CL, Lee GH, Dan YY, Chan YS, Lim SG, Chan JKY, Chandy KG, Chen Q.
Her Z, et al. Among authors: tan jhl.
Front Immunol. 2020 Sep 11;11:580968. doi: 10.3389/fimmu.2020.580968. eCollection 2020.
Front Immunol. 2020.
PMID: 33013934
Free PMC article.
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Discovery of a Novel Mycobacterial F-ATP Synthase Inhibitor and its Potency in Combination with Diarylquinolines.
Hotra A, Ragunathan P, Ng PS, Seankongsuk P, Harikishore A, Sarathy JP, Saw WG, Lakshmanan U, Sae-Lao P, Kalia NP, Shin J, Kalyanasundaram R, Anbarasu S, Parthasarathy K, Pradeep CN, Makhija H, Dröge P, Poulsen A, Tan JHL, Pethe K, Dick T, Bates RW, Grüber G.
Hotra A, et al. Among authors: tan jhl.
Angew Chem Int Ed Engl. 2020 Aug 3;59(32):13295-13304. doi: 10.1002/anie.202002546. Epub 2020 May 26.
Angew Chem Int Ed Engl. 2020.
PMID: 32337801
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Infertility-Causing Haploinsufficiency Reveals TRIM28/KAP1 Requirement in Spermatogonia.
Tan JHL, Wollmann H, van Pelt AMM, Kaldis P, Messerschmidt DM.
Tan JHL, et al.
Stem Cell Reports. 2020 May 12;14(5):818-827. doi: 10.1016/j.stemcr.2020.03.013. Epub 2020 Apr 16.
Stem Cell Reports. 2020.
PMID: 32302554
Free PMC article.
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CDK2 regulates the NRF1/Ehmt1 axis during meiotic prophase I.
Palmer N, Talib SZA, Ratnacaram CK, Low D, Bisteau X, Lee JHS, Pfeiffenberger E, Wollmann H, Tan JHL, Wee S, Sobota R, Gunaratne J, Messerschmidt DM, Guccione E, Kaldis P.
Palmer N, et al. Among authors: tan jhl.
J Cell Biol. 2019 Sep 2;218(9):2896-2918. doi: 10.1083/jcb.201903125. Epub 2019 Jul 26.
J Cell Biol. 2019.
PMID: 31350280
Free PMC article.
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Loss of maternal Trim28 causes male-predominant early embryonic lethality.
Sampath Kumar A, Seah MK, Ling KY, Wang Y, Tan JH, Nitsch S, Lim SL, Lorthongpanich C, Wollmann H, Low DH, Guccione E, Messerschmidt DM.
Sampath Kumar A, et al.
Genes Dev. 2017 Jan 1;31(1):12-17. doi: 10.1101/gad.291195.116. Epub 2017 Jan 23.
Genes Dev. 2017.
PMID: 28115466
Free PMC article.
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