Liu H - Search Results

1

Discovery and Development of S6821 and S7958 as Potent TAS2R8 Antagonists.

Fotsing JR, Darmohusodo V, Patron AP, Ching BW, Brady T, Arellano M, Chen Q, Davis TJ, Liu H, Servant G, Zhang L, Williams M, Saganich M, Ditschun T, Tachdjian C, Karanewsky DS. Fotsing JR, et al. Among authors: liu h. J Med Chem. 2020 May 14;63(9):4957-4977. doi: 10.1021/acs.jmedchem.0c00388. Epub 2020 Apr 24. J Med Chem. 2020. PMID: 32330040

2

Discovery and development of a novel class of phenoxyacetyl amides as highly potent TRPM8 agonists for use as cooling agents.

Noncovich A, Priest C, Ung J, Patron AP, Servant G, Brust P, Servant N, Faber N, Liu H, Gonsalves NS, Ditschun TL. Noncovich A, et al. Among authors: liu h. Bioorg Med Chem Lett. 2017 Aug 15;27(16):3931-3938. doi: 10.1016/j.bmcl.2017.04.003. Epub 2017 Apr 11. Bioorg Med Chem Lett. 2017. PMID: 28662813

3

Toxicological evaluation of two novel bitter modifying flavour compounds: 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)imidazolidine-2,4-dione and 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)-5,5-dimethylimidazolidine-2,4-dione.

Karanewsky DS, Arthur AJ, Liu H, Chi B, Ida L, Markison S. Karanewsky DS, et al. Among authors: liu h. Toxicol Rep. 2016 Feb 28;3:310-327. doi: 10.1016/j.toxrep.2016.02.007. eCollection 2016. Toxicol Rep. 2016. PMID: 28959552 Free PMC article.

4

Toxicological evaluation of the flavour ingredient N-(1-((4-amino-2,2-dioxido-1H-benzo[c][1,2,6]thiadiazin-5-yl)oxy)-2-methylpropan-2-yl)-2,6-dimethylisonicotinamide (S2218).

Karanewsky DS, Servant G, Liu H, Chi B, Ida L, Saganich M, Werner S, Fotsing JR, Patron A, Tachdjian C, Arthur A. Karanewsky DS, et al. Among authors: liu h. Toxicol Rep. 2017 Sep 14;4:507-520. doi: 10.1016/j.toxrep.2017.09.004. eCollection 2017. Toxicol Rep. 2017. PMID: 28959681 Free PMC article.

5

Exploiting adduct formation through an auxiliary spray in liquid chromatography-electrospray ionization mass spectrometry to improve charge-carrier identification.

Liu H, Patron A, Wang Y, Dasgupta PK. Liu H, et al. J Chromatogr A. 2020 Nov 22;1632:461601. doi: 10.1016/j.chroma.2020.461601. Epub 2020 Oct 10. J Chromatogr A. 2020. PMID: 33069953

6

Toxicological evaluation and metabolism of two N-alkyl benzamide umami flavour compounds: N-(heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide and (R)-N-(1-methoxy-4-methylpentan-2-yl)-3,4-dimethylbenzamide.

Karanewsky DS, Arthur AJ, Liu H, Chi B, Ida L. Karanewsky DS, et al. Among authors: liu h. Toxicol Rep. 2016 Oct 29;3:841-860. doi: 10.1016/j.toxrep.2016.10.008. eCollection 2016. Toxicol Rep. 2016. PMID: 28959612 Free PMC article.

7

Toxicological evaluation of the flavour ingredient 4-amino-5-(3-(isopropylamino)-2,2-dimethyl-3-oxopropoxy)-2-methylquinoline-3-carboxylic acid.

Arthur AJ, Karanewsky DS, Liu H, Chi B, Markison S. Arthur AJ, et al. Among authors: liu h. Toxicol Rep. 2015 Sep 3;2:1255-1264. doi: 10.1016/j.toxrep.2015.08.012. eCollection 2015. Toxicol Rep. 2015. PMID: 28962468 Free PMC article.

8

Toxicological evaluation of a novel cooling compound: 2-(4-methylphenoxy)-N-(1H-pyrazol-3-yl)-N-(2-thienylmethyl)acetamide.

Karanewsky DS, Arthur AJ, Liu H, Chi B, Markison S. Karanewsky DS, et al. Among authors: liu h. Toxicol Rep. 2015 Sep 11;2:1291-1309. doi: 10.1016/j.toxrep.2015.09.001. eCollection 2015. Toxicol Rep. 2015. PMID: 28962472 Free PMC article.

9

Toxicological evaluation of a novel umami flavour compound: 2-(((3-(2,3-Dimethoxyphenyl)-1H-1,2,4-triazol-5-yl)thio)methyl)pyridine.

Karanewsky DS, Arthur AJ, Liu H, Chi B, Ida L, Markison S. Karanewsky DS, et al. Among authors: liu h. Toxicol Rep. 2016 May 18;3:501-512. doi: 10.1016/j.toxrep.2016.05.002. eCollection 2016. Toxicol Rep. 2016. PMID: 28959573 Free PMC article.

10

Transient Ion-Pair Separations for Electrospray Mass Spectrometry.

Liu H, Lam L, Chi B, Kadjo AF, Dasgupta PK. Liu H, et al. Anal Chem. 2016 Feb 16;88(4):2059-64. doi: 10.1021/acs.analchem.5b03202. Epub 2016 Jan 27. Anal Chem. 2016. PMID: 26765166

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