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Identification of novel benzimidazole derivatives as inhibitors of leukotriene biosynthesis by virtual screening targeting 5-lipoxygenase-activating protein (FLAP).
Banoglu E, Çalişkan B, Luderer S, Eren G, Özkan Y, Altenhofen W, Weinigel C, Barz D, Gerstmeier J, Pergola C, Werz O. Banoglu E, et al. Among authors: gerstmeier j. Bioorg Med Chem. 2012 Jun 15;20(12):3728-41. doi: 10.1016/j.bmc.2012.04.048. Epub 2012 May 1. Bioorg Med Chem. 2012. PMID: 22607880
Imbricaric acid and perlatolic acid: multi-targeting anti-inflammatory depsides from Cetrelia monachorum.
Oettl SK, Gerstmeier J, Khan SY, Wiechmann K, Bauer J, Atanasov AG, Malainer C, Awad EM, Uhrin P, Heiss EH, Waltenberger B, Remias D, Breuss JM, Boustie J, Dirsch VM, Stuppner H, Werz O, Rollinger JM. Oettl SK, et al. Among authors: gerstmeier j. PLoS One. 2013 Oct 9;8(10):e76929. doi: 10.1371/journal.pone.0076929. eCollection 2013. PLoS One. 2013. PMID: 24130812 Free PMC article.
The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP).
Pergola C, Gerstmeier J, Mönch B, Çalışkan B, Luderer S, Weinigel C, Barz D, Maczewsky J, Pace S, Rossi A, Sautebin L, Banoglu E, Werz O. Pergola C, et al. Among authors: gerstmeier j. Br J Pharmacol. 2014 Jun;171(12):3051-64. doi: 10.1111/bph.12625. Br J Pharmacol. 2014. PMID: 24641614 Free PMC article.
54 results