Wang X - Search Results

1

Targeting mir128-3p alleviates myocardial insulin resistance and prevents ischemia-induced heart failure.

Ruiz-Velasco A, Zi M, Hille SS, Azam T, Kaur N, Jiang J, Nguyen B, Sekeres K, Binder P, Collins L, Pu F, Xiao H, Guan K, Frey N, Cartwright EJ, Müller OJ, Wang X, Liu W. Ruiz-Velasco A, et al. Among authors: wang x. Elife. 2020 Mar 30;9:e54298. doi: 10.7554/eLife.54298. Elife. 2020. PMID: 32223896 Free PMC article.

2

Targeted deletion of mek5 causes early embryonic death and defects in the extracellular signal-regulated kinase 5/myocyte enhancer factor 2 cell survival pathway.

Wang X, Merritt AJ, Seyfried J, Guo C, Papadakis ES, Finegan KG, Kayahara M, Dixon J, Boot-Handford RP, Cartwright EJ, Mayer U, Tournier C. Wang X, et al. Mol Cell Biol. 2005 Jan;25(1):336-45. doi: 10.1128/MCB.25.1.336-345.2005. Mol Cell Biol. 2005. PMID: 15601854 Free PMC article.

3

Cardiac-specific deletion of mkk4 reveals its role in pathological hypertrophic remodeling but not in physiological cardiac growth.

Liu W, Zi M, Jin J, Prehar S, Oceandy D, Kimura TE, Lei M, Neyses L, Weston AH, Cartwright EJ, Wang X. Liu W, et al. Among authors: wang x. Circ Res. 2009 Apr 10;104(7):905-14. doi: 10.1161/CIRCRESAHA.108.188292. Epub 2009 Mar 5. Circ Res. 2009. PMID: 19265040

4

Targeted deletion of the extracellular signal-regulated protein kinase 5 attenuates hypertrophic response and promotes pressure overload-induced apoptosis in the heart.

Kimura TE, Jin J, Zi M, Prehar S, Liu W, Oceandy D, Abe J, Neyses L, Weston AH, Cartwright EJ, Wang X. Kimura TE, et al. Among authors: wang x. Circ Res. 2010 Mar 19;106(5):961-70. doi: 10.1161/CIRCRESAHA.109.209320. Epub 2010 Jan 14. Circ Res. 2010. PMID: 20075332 Free PMC article.

5

Deprivation of MKK7 in cardiomyocytes provokes heart failure in mice when exposed to pressure overload.

Liu W, Zi M, Chi H, Jin J, Prehar S, Neyses L, Cartwright EJ, Flavell RA, Davis RJ, Wang X. Liu W, et al. Among authors: wang x. J Mol Cell Cardiol. 2011 Apr;50(4):702-11. doi: 10.1016/j.yjmcc.2011.01.013. Epub 2011 Jan 31. J Mol Cell Cardiol. 2011. PMID: 21284947

6

Mitogen-activated protein kinase kinase 4 deficiency in cardiomyocytes causes connexin 43 reduction and couples hypertrophic signals to ventricular arrhythmogenesis.

Zi M, Kimura TE, Liu W, Jin J, Higham J, Kharche S, Hao G, Shi Y, Shen W, Prehar S, Mironov A, Neyses L, Bierhuizen MF, Boyett MR, Zhang H, Lei M, Cartwright EJ, Wang X. Zi M, et al. Among authors: wang x. J Biol Chem. 2011 May 20;286(20):17821-30. doi: 10.1074/jbc.M111.228791. Epub 2011 Mar 28. J Biol Chem. 2011. PMID: 21454599 Free PMC article. No abstract available.

7

Activation of Pak1/Akt/eNOS signaling following sphingosine-1-phosphate release as part of a mechanism protecting cardiomyocytes against ischemic cell injury.

Egom EE, Mohamed TM, Mamas MA, Shi Y, Liu W, Chirico D, Stringer SE, Ke Y, Shaheen M, Wang T, Chacko S, Wang X, Solaro RJ, Fath-Ordoubadi F, Cartwright EJ, Lei M. Egom EE, et al. Among authors: wang x, wang t. Am J Physiol Heart Circ Physiol. 2011 Oct;301(4):H1487-95. doi: 10.1152/ajpheart.01003.2010. Epub 2011 Jun 24. Am J Physiol Heart Circ Physiol. 2011. PMID: 21705677 Free PMC article.

8

Pak1 as a novel therapeutic target for antihypertrophic treatment in the heart.

Liu W, Zi M, Naumann R, Ulm S, Jin J, Taglieri DM, Prehar S, Gui J, Tsui H, Xiao RP, Neyses L, Solaro RJ, Ke Y, Cartwright EJ, Lei M, Wang X. Liu W, et al. Among authors: wang x. Circulation. 2011 Dec 13;124(24):2702-15. doi: 10.1161/CIRCULATIONAHA.111.048785. Epub 2011 Nov 14. Circulation. 2011. PMID: 22082674 Free PMC article.

9

A novel immunomodulator, FTY-720 reverses existing cardiac hypertrophy and fibrosis from pressure overload by targeting NFAT (nuclear factor of activated T-cells) signaling and periostin.

Liu W, Zi M, Tsui H, Chowdhury SK, Zeef L, Meng QJ, Travis M, Prehar S, Berry A, Hanley NA, Neyses L, Xiao RP, Oceandy D, Ke Y, Solaro RJ, Cartwright EJ, Lei M, Wang X. Liu W, et al. Among authors: wang x. Circ Heart Fail. 2013 Jul;6(4):833-44. doi: 10.1161/CIRCHEARTFAILURE.112.000123. Epub 2013 Jun 10. Circ Heart Fail. 2013. PMID: 23753531 Free PMC article.

10

Targeted deletion of ERK2 in cardiomyocytes attenuates hypertrophic response but provokes pathological stress induced cardiac dysfunction.

Ulm S, Liu W, Zi M, Tsui H, Chowdhury SK, Endo S, Satoh Y, Prehar S, Wang R, Cartwright EJ, Wang X. Ulm S, et al. Among authors: wang x, wang r. J Mol Cell Cardiol. 2014 Jul;72(100):104-16. doi: 10.1016/j.yjmcc.2014.03.002. Epub 2014 Mar 12. J Mol Cell Cardiol. 2014. PMID: 24631771 Free PMC article.

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