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PAICS, a De Novo Purine Biosynthetic Enzyme, Is Overexpressed in Pancreatic Cancer and Is Involved in Its Progression.
Agarwal S, Chakravarthi BVSK, Kim HG, Gupta N, Hale K, Balasubramanya SAH, Oliver PG, Thomas DG, Eltoum IA, Buchsbaum DJ, Manne U, Varambally S. Agarwal S, et al. Among authors: chakravarthi bvsk. Transl Oncol. 2020 Jul;13(7):100776. doi: 10.1016/j.tranon.2020.100776. Epub 2020 May 15. Transl Oncol. 2020. PMID: 32422575 Free PMC article.
Expression and Role of PAICS, a De Novo Purine Biosynthetic Gene in Prostate Cancer.
Chakravarthi BV, Goswami MT, Pathi SS, Dodson M, Chandrashekar DS, Agarwal S, Nepal S, Hodigere Balasubramanya SA, Siddiqui J, Lonigro RJ, Chinnaiyan AM, Kunju LP, Palanisamy N, Varambally S. Chakravarthi BV, et al. Prostate. 2017 Jan;77(1):10-21. doi: 10.1002/pros.23243. Epub 2016 Aug 22. Prostate. 2017. PMID: 27550065 Free article.
miR-34a Regulates Expression of the Stathmin-1 Oncoprotein and Prostate Cancer Progression.
Chakravarthi BVSK, Chandrashekar DS, Agarwal S, Balasubramanya SAH, Pathi SS, Goswami MT, Jing X, Wang R, Mehra R, Asangani IA, Chinnaiyan AM, Manne U, Sonpavde G, Netto GJ, Gordetsky J, Varambally S. Chakravarthi BVSK, et al. Mol Cancer Res. 2018 Jul;16(7):1125-1137. doi: 10.1158/1541-7786.MCR-17-0230. Epub 2017 Oct 12. Mol Cancer Res. 2018. PMID: 29025958 Free PMC article.
Expression and role of PAICS, a de novo purine biosynthetic gene in prostate cancer.
Chakravarthi BVSK, Goswami MT, Pathi SS, Dodson M, Chandrashekar DS, Agarwal S, Nepal S, Hodigere Balasubramanya SA, Siddiqui J, Lonigro RJ, Chinnaiyan AM, Kunju LP, Palanisamy N, Varambally S. Chakravarthi BVSK, et al. Prostate. 2018 Jun;78(9):693-694. doi: 10.1002/pros.23533. Epub 2018 Apr 10. Prostate. 2018. PMID: 29744932 Free article. No abstract available.
A Role for De Novo Purine Metabolic Enzyme PAICS in Bladder Cancer Progression.
Chakravarthi BVSK, Rodriguez Pena MDC, Agarwal S, Chandrashekar DS, Hodigere Balasubramanya SA, Jabboure FJ, Matoso A, Bivalacqua TJ, Rezaei K, Chaux A, Grizzle WE, Sonpavde G, Gordetsky J, Netto GJ, Varambally S. Chakravarthi BVSK, et al. Neoplasia. 2018 Sep;20(9):894-904. doi: 10.1016/j.neo.2018.07.006. Epub 2018 Aug 15. Neoplasia. 2018. PMID: 30121007 Free PMC article.
Targeting P4HA1 with a Small Molecule Inhibitor in a Colorectal Cancer PDX Model.
Agarwal S, Behring M, Kim HG, Bajpai P, Chakravarthi BVSK, Gupta N, Elkholy A, Al Diffalha S, Varambally S, Manne U. Agarwal S, et al. Among authors: chakravarthi bvsk. Transl Oncol. 2020 Apr;13(4):100754. doi: 10.1016/j.tranon.2020.100754. Epub 2020 Mar 18. Transl Oncol. 2020. PMID: 32199274 Free PMC article.
Therapeutically actionable PAK4 is amplified, overexpressed, and involved in bladder cancer progression.
Chandrashekar DS, Chakravarthi BVSK, Robinson AD, Anderson JC, Agarwal S, Balasubramanya SAH, Eich ML, Bajpai AK, Davuluri S, Guru MS, Guru AS, Naik G, Della Manna DL, Acharya KK, Carskadon S, Manne U, Crossman DK, Ferguson JE, Grizzle WE, Palanisamy N, Willey CD, Crowley MR, Netto GJ, Yang ES, Varambally S, Sonpavde G. Chandrashekar DS, et al. Among authors: chakravarthi bvsk. Oncogene. 2020 May;39(20):4077-4091. doi: 10.1038/s41388-020-1275-7. Epub 2020 Mar 30. Oncogene. 2020. PMID: 32231273
Collagen modifying enzyme P4HA1 is overexpressed and plays a role in lung adenocarcinoma.
Robinson AD, Chakravarthi BVSK, Agarwal S, Chandrashekar DS, Davenport ML, Chen G, Manne U, Beer DG, Edmonds MD, Varambally S. Robinson AD, et al. Among authors: chakravarthi bvsk. Transl Oncol. 2021 Aug;14(8):101128. doi: 10.1016/j.tranon.2021.101128. Epub 2021 May 25. Transl Oncol. 2021. PMID: 34049151 Free PMC article.
31 results