Heidel FH - Search Results

1

SIRT7: an influence factor in healthy aging and the development of age-dependent myeloid stem-cell disorders.

Kaiser A, Schmidt M, Huber O, Frietsch JJ, Scholl S, Heidel FH, Hochhaus A, Müller JP, Ernst T. Kaiser A, et al. Among authors: heidel fh. Leukemia. 2020 Aug;34(8):2206-2216. doi: 10.1038/s41375-020-0803-3. Epub 2020 Mar 25. Leukemia. 2020. PMID: 32214204 Free PMC article.

2

The kinase inhibitor LS104 induces apoptosis, enhances cytotoxic effects of chemotherapeutic drugs and is targeting the receptor tyrosine kinase FLT3 in acute myeloid leukemia.

Kasper S, Breitenbuecher F, Hoehn Y, Heidel F, Lipka DB, Markova B, Huber C, Kindler T, Fischer T. Kasper S, et al. Leuk Res. 2008 Nov;32(11):1698-708. doi: 10.1016/j.leukres.2008.05.003. Epub 2008 Jun 16. Leuk Res. 2008. PMID: 18556063

3

Ponatinib may overcome resistance of FLT3-ITD harbouring additional point mutations, notably the previously refractory F691I mutation.

Zirm E, Spies-Weisshart B, Heidel F, Schnetzke U, Böhmer FD, Hochhaus A, Fischer T, Scholl S. Zirm E, et al. Br J Haematol. 2012 May;157(4):483-92. doi: 10.1111/j.1365-2141.2012.09085.x. Epub 2012 Mar 13. Br J Haematol. 2012. PMID: 22409268 Free article.

4

Expression of protein-tyrosine phosphatases in Acute Myeloid Leukemia cells: FLT3 ITD sustains high levels of DUSP6 expression.

Arora D, Köthe S, van den Eijnden M, Hooft van Huijsduijnen R, Heidel F, Fischer T, Scholl S, Tölle B, Böhmer SA, Lennartsson J, Isken F, Müller-Tidow C, Böhmer FD. Arora D, et al. Cell Commun Signal. 2012 Jul 11;10(1):19. doi: 10.1186/1478-811X-10-19. Cell Commun Signal. 2012. PMID: 22784513 Free PMC article.

5

NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells.

Jayavelu AK, Müller JP, Bauer R, Böhmer SA, Lässig J, Cerny-Reiterer S, Sperr WR, Valent P, Maurer B, Moriggl R, Schröder K, Shah AM, Fischer M, Scholl S, Barth J, Oellerich T, Berg T, Serve H, Frey S, Fischer T, Heidel FH, Böhmer FD. Jayavelu AK, et al. Among authors: heidel fh. Leukemia. 2016 Feb;30(2):473-83. doi: 10.1038/leu.2015.234. Epub 2015 Aug 26. Leukemia. 2016. PMID: 26308771

6

Pomalidomide in myeloproliferative neoplasm-associated myelofibrosis.

Schlenk RF, Stegelmann F, Reiter A, Jost E, Gattermann N, Hebart H, Waller C, Hochhaus A, Platzbecker U, Schafhausen P, Blau IW, Verbeek W, Heidel FH, Werner M, Kreipe H, Teleanu V, Benner A, Döhner H, Grießhammer M, Döhner K. Schlenk RF, et al. Among authors: heidel fh. Leukemia. 2017 Apr;31(4):889-895. doi: 10.1038/leu.2016.299. Epub 2016 Oct 24. Leukemia. 2017. PMID: 27774990 Clinical Trial.

7

Kinomics Screening Identifies Aberrant Phosphorylation of CDC25C in FLT3-ITD-positive AML.

Perner F, Schnöder TM, Fischer T, Heidel FH. Perner F, et al. Among authors: heidel fh. Anticancer Res. 2016 Dec;36(12):6249-6258. doi: 10.21873/anticanres.11219. Anticancer Res. 2016. PMID: 27919943

8

Gain of function in Jak2^V617F-positive T-cells.

Nishanth G, Wolleschak D, Fahldieck C, Fischer T, Mullally A, Perner F, Schnöder TM, Just S, Heidel FH, Schlüter D. Nishanth G, et al. Among authors: heidel fh. Leukemia. 2017 Apr;31(4):1000-1003. doi: 10.1038/leu.2017.6. Epub 2017 Jan 11. Leukemia. 2017. PMID: 28074070 No abstract available.

9

JAK2-V617F activates β1-integrin-mediated adhesion of granulocytes to vascular cell adhesion molecule 1.

Gupta N, Edelmann B, Schnoeder TM, Saalfeld FC, Wolleschak D, Kliche S, Schraven B, Heidel FH, Fischer T. Gupta N, et al. Among authors: heidel fh. Leukemia. 2017 May;31(5):1223-1226. doi: 10.1038/leu.2017.26. Epub 2017 Jan 18. Leukemia. 2017. PMID: 28096537 Free PMC article. No abstract available.

10

Synergistic killing of FLT3ITD-positive AML cells by combined inhibition of tyrosine-kinase activity and N-glycosylation.

Tsitsipatis D, Jayavelu AK, Müller JP, Bauer R, Schmidt-Arras D, Mahboobi S, Schnöder TM, Heidel F, Böhmer FD. Tsitsipatis D, et al. Oncotarget. 2017 Apr 18;8(16):26613-26624. doi: 10.18632/oncotarget.15772. Oncotarget. 2017. PMID: 28460451 Free PMC article.

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