Nunes RJ - Search Results

1

Aldehyde biphenyl chalcones induce immunogenic apoptotic-like cell death and are promising new safe compounds against a wide range of hematologic cancers.

Maioral MF, Stefanes NM, Neuenfeldt PD, Chiaradia-Delatorre LD, Nunes RJ, Santos-Silva MC. Maioral MF, et al. Among authors: nunes rj. Future Med Chem. 2020 Apr;12(8):673-688. doi: 10.4155/fmc-2019-0228. Epub 2020 Mar 19. Future Med Chem. 2020. PMID: 32191531

2

Synthesis and pharmacological activity of chalcones derived from 2,4,6-trimethoxyacetophenone in RAW 264.7 cells stimulated by LPS: quantitative structure-activity relationships.

Chiaradia LD, dos Santos R, Vitor CE, Vieira AA, Leal PC, Nunes RJ, Calixto JB, Yunes RA. Chiaradia LD, et al. Among authors: nunes rj. Bioorg Med Chem. 2008 Jan 15;16(2):658-67. doi: 10.1016/j.bmc.2007.10.039. Epub 2007 Oct 18. Bioorg Med Chem. 2008. PMID: 17988874

3

Synthesis, biological evaluation and SAR of sulfonamide 4-methoxychalcone derivatives with potential antileishmanial activity.

Andrighetti-Fröhner CR, de Oliveira KN, Gaspar-Silva D, Pacheco LK, Joussef AC, Steindel M, Simões CM, de Souza AM, Magalhaes UO, Afonso IF, Rodrigues CR, Nunes RJ, Castro HC. Andrighetti-Fröhner CR, et al. Among authors: nunes rj. Eur J Med Chem. 2009 Feb;44(2):755-63. doi: 10.1016/j.ejmech.2008.04.016. Epub 2008 May 6. Eur J Med Chem. 2009. PMID: 18554753

4

Synthetic chalcones as efficient inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase PtpA.

Chiaradia LD, Mascarello A, Purificação M, Vernal J, Cordeiro MN, Zenteno ME, Villarino A, Nunes RJ, Yunes RA, Terenzi H. Chiaradia LD, et al. Among authors: nunes rj. Bioorg Med Chem Lett. 2008 Dec 1;18(23):6227-30. doi: 10.1016/j.bmcl.2008.09.105. Epub 2008 Oct 5. Bioorg Med Chem Lett. 2008. PMID: 18930396

5

Hydroxychalcones induce apoptosis in B16-F10 melanoma cells via GSH and ATP depletion.

Navarini AL, Chiaradia LD, Mascarello A, Fritzen M, Nunes RJ, Yunes RA, Creczynski-Pasa TB. Navarini AL, et al. Among authors: nunes rj. Eur J Med Chem. 2009 Apr;44(4):1630-7. doi: 10.1016/j.ejmech.2008.09.009. Epub 2008 Sep 19. Eur J Med Chem. 2009. PMID: 19211173

6

Inhibition of Mycobacterium tuberculosis tyrosine phosphatase PtpA by synthetic chalcones: kinetics, molecular modeling, toxicity and effect on growth.

Mascarello A, Chiaradia LD, Vernal J, Villarino A, Guido RV, Perizzolo P, Poirier V, Wong D, Martins PG, Nunes RJ, Yunes RA, Andricopulo AD, Av-Gay Y, Terenzi H. Mascarello A, et al. Among authors: nunes rj. Bioorg Med Chem. 2010 Jun 1;18(11):3783-9. doi: 10.1016/j.bmc.2010.04.051. Epub 2010 Apr 21. Bioorg Med Chem. 2010. PMID: 20462762 Free article.

7

Induction of apoptosis and cell cycle arrest in L-1210 murine lymphoblastic leukaemia cells by (2E)-3-(2-naphthyl)-1-(3'-methoxy-4'-hydroxy-phenyl)-2-propen-1-one.

Pedrini FS, Chiaradia LD, Licínio MA, de Moraes AC, Curta JC, Costa A, Mascarello A, Creczinsky-Pasa TB, Nunes RJ, Yunes RA, Santos-Silva MC. Pedrini FS, et al. Among authors: nunes rj. J Pharm Pharmacol. 2010 Sep;62(9):1128-36. doi: 10.1111/j.2042-7158.2010.01141.x. J Pharm Pharmacol. 2010. PMID: 20796191

8

Naphthylchalcones induce apoptosis and caspase activation in a leukemia cell line: The relationship between mitochondrial damage, oxidative stress, and cell death.

Winter E, Chiaradia LD, de Cordova CA, Nunes RJ, Yunes RA, Creczynski-Pasa TB. Winter E, et al. Among authors: nunes rj. Bioorg Med Chem. 2010 Nov 15;18(22):8026-34. doi: 10.1016/j.bmc.2010.09.025. Epub 2010 Sep 16. Bioorg Med Chem. 2010. PMID: 20952199 Free article.

9

Evaluation of apoptotic effect of cyclic imide derivatives on murine B16F10 melanoma cells.

Machado KE, Oliveira KN, Santos-Bubniak L, Licínio MA, Nunes RJ, Santos-Silva MC. Machado KE, et al. Among authors: nunes rj. Bioorg Med Chem. 2011 Nov 1;19(21):6285-91. doi: 10.1016/j.bmc.2011.09.008. Epub 2011 Sep 10. Bioorg Med Chem. 2011. PMID: 21964182

10

Synthesis, biological evaluation, and molecular modeling of chalcone derivatives as potent inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatases (PtpA and PtpB).

Chiaradia LD, Martins PG, Cordeiro MN, Guido RV, Ecco G, Andricopulo AD, Yunes RA, Vernal J, Nunes RJ, Terenzi H. Chiaradia LD, et al. Among authors: nunes rj. J Med Chem. 2012 Jan 12;55(1):390-402. doi: 10.1021/jm2012062. Epub 2011 Dec 20. J Med Chem. 2012. PMID: 22136336

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