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Page 1
The Key Characteristics of Carcinogens: Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them.
Smith MT, Guyton KZ, Kleinstreuer N, Borrel A, Cardenas A, Chiu WA, Felsher DW, Gibbons CF, Goodson WH 3rd, Houck KA, Kane AB, La Merrill MA, Lebrec H, Lowe L, McHale CM, Minocherhomji S, Rieswijk L, Sandy MS, Sone H, Wang A, Zhang L, Zeise L, Fielden M. Smith MT, et al. Among authors: gibbons cf. Cancer Epidemiol Biomarkers Prev. 2020 Oct;29(10):1887-1903. doi: 10.1158/1055-9965.EPI-19-1346. Epub 2020 Mar 9. Cancer Epidemiol Biomarkers Prev. 2020. PMID: 32152214 Free PMC article.
Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis.
Smith MT, Guyton KZ, Gibbons CF, Fritz JM, Portier CJ, Rusyn I, DeMarini DM, Caldwell JC, Kavlock RJ, Lambert PF, Hecht SS, Bucher JR, Stewart BW, Baan RA, Cogliano VJ, Straif K. Smith MT, et al. Among authors: gibbons cf. Environ Health Perspect. 2016 Jun;124(6):713-21. doi: 10.1289/ehp.1509912. Epub 2015 Nov 24. Environ Health Perspect. 2016. PMID: 26600562 Free PMC article.
Proposed Key Characteristics of Male Reproductive Toxicants as an Approach for Organizing and Evaluating Mechanistic Evidence in Human Health Hazard Assessments.
Arzuaga X, Smith MT, Gibbons CF, Skakkebæk NE, Yost EE, Beverly BEJ, Hotchkiss AK, Hauser R, Pagani RL, Schrader SM, Zeise L, Prins GS. Arzuaga X, et al. Among authors: gibbons cf. Environ Health Perspect. 2019 Jun;127(6):65001. doi: 10.1289/EHP5045. Epub 2019 Jun 14. Environ Health Perspect. 2019. PMID: 31199676 Free PMC article.
Evaluation of Existing QSAR Models and Structural Alerts and Development of New Ensemble Models for Genotoxicity Using a Newly Compiled Experimental Dataset.
Pradeep P, Judson R, DeMarini DM, Keshava N, Martin TM, Dean J, Gibbons CF, Simha A, Warren SH, Gwinn MR, Patlewicz G. Pradeep P, et al. Among authors: gibbons cf. Comput Toxicol. 2021 May 1;18:10.1016/j.comtox.2021.100167. doi: 10.1016/j.comtox.2021.100167. Comput Toxicol. 2021. PMID: 34504984 Free PMC article.
Integrating publicly available information to screen potential candidates for chemical prioritization under the Toxic Substances Control Act: A proof of concept case study using genotoxicity and carcinogenicity.
Patlewicz G, Dean JL, Gibbons CF, Judson RS, Keshava N, Vegosen L, Martin TM, Pradeep P, Simha A, Warren SH, Gwinn MR, DeMarini DM. Patlewicz G, et al. Among authors: gibbons cf. Comput Toxicol. 2021 Nov 1;20:1-100185. doi: 10.1016/j.comtox.2021.100185. Comput Toxicol. 2021. PMID: 35128218 Free PMC article.
Applied genetic toxicology: From principles to practice.
Gibbons CF, LeBaron MJ. Gibbons CF, et al. Environ Mol Mutagen. 2017 Jun;58(5):232-234. doi: 10.1002/em.22106. Environ Mol Mutagen. 2017. PMID: 28621032 Free PMC article. No abstract available.
Applying evidence-based methods to the development and use of adverse outcome pathways.
De Vries RBM, Angrish M, Browne P, Brozek J, Rooney AA, Wikoff DS, Whaley P, Edwards SW, Morgan RL, Druwe IL, Hoffmann S, Hartung T, Thayer K, Avey MT, Beverly BEJ, Falavigna M, Gibbons C, Goyak K, Kraft A, Nampo F, Qaseem A, Sears M, Singh JA, Willett C, Yost EY, Schünemann H, Tsaioun K. De Vries RBM, et al. ALTEX. 2021;38(2):336-347. doi: 10.14573/altex.2101211. Epub 2021 Apr 8. ALTEX. 2021. PMID: 33837437 Free PMC article.
Use of systematic evidence maps within the US environmental protection agency (EPA) integrated risk information system (IRIS) program: Advancements to date and looking ahead.
Thayer KA, Shaffer RM, Angrish M, Arzuaga X, Carlson LM, Davis A, Dishaw L, Druwe I, Gibbons C, Glenn B, Jones R, Kaiser JP, Keshava C, Keshava N, Kraft A, Lizarraga L, Markey K, Persad A, Radke EG, Rice G, Schulz B, Shannon T, Shapiro A, Thacker S, Vulimiri S, Woodall G, Yost E. Thayer KA, et al. Environ Int. 2022 Nov;169:107363. doi: 10.1016/j.envint.2022.107363. Epub 2022 Aug 31. Environ Int. 2022. PMID: 36057470 Free article.
Systematic evidence map (SEM) template: Report format and methods used for the US EPA Integrated Risk Information System (IRIS) program, Provisional Peer Reviewed Toxicity Value (PPRTV) program, and other "fit for purpose" literature-based human health analyses.
Thayer KA, Angrish M, Arzuaga X, Carlson LM, Davis A, Dishaw L, Druwe I, Gibbons C, Glenn B, Jones R, Phillip Kaiser J, Keshava C, Keshava N, Kraft A, Lizarraga L, Persad A, Radke EG, Rice G, Schulz B, Shaffer RM, Shannon T, Shapiro A, Thacker S, Vulimiri SV, Williams AJ, Woodall G, Yost E, Blain R, Duke K, Goldstone AE, Hartman P, Hobbie K, Ingle B, Lemeris C, Lin C, Lindahl A, McKinley K, Soleymani P, Vetter N. Thayer KA, et al. Environ Int. 2022 Nov;169:107468. doi: 10.1016/j.envint.2022.107468. Epub 2022 Aug 13. Environ Int. 2022. PMID: 36174483 Free article.
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