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Targeting AML-associated FLT3 mutations with a type I kinase inhibitor.
Jones LM, Melgar K, Bolanos L, Hueneman K, Walker MM, Jiang JK, Wilson KM, Zhang X, Shen J, Jiang F, Sutter P, Wang A, Xu X, Tawa GJ, Hoyt SB, Wunderlich M, O'Brien E, Perentesis JP, Starczynowski DT, Thomas CJ. Jones LM, et al. Among authors: starczynowski dt. J Clin Invest. 2020 Apr 1;130(4):2017-2023. doi: 10.1172/JCI127907. J Clin Invest. 2020. PMID: 32149729 Free PMC article.
Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1.
Fang J, Rhyasen G, Bolanos L, Rasch C, Varney M, Wunderlich M, Goyama S, Jansen G, Cloos J, Rigolino C, Cortelezzi A, Mulloy JC, Oliva EN, Cuzzola M, Starczynowski DT. Fang J, et al. Among authors: starczynowski dt. Blood. 2012 Jul 26;120(4):858-67. doi: 10.1182/blood-2012-02-407999. Epub 2012 Jun 8. Blood. 2012. PMID: 22685174 Free PMC article.
Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome.
Rhyasen GW, Bolanos L, Fang J, Jerez A, Wunderlich M, Rigolino C, Mathews L, Ferrer M, Southall N, Guha R, Keller J, Thomas C, Beverly LJ, Cortelezzi A, Oliva EN, Cuzzola M, Maciejewski JP, Mulloy JC, Starczynowski DT. Rhyasen GW, et al. Among authors: starczynowski dt. Cancer Cell. 2013 Jul 8;24(1):90-104. doi: 10.1016/j.ccr.2013.05.006. Cancer Cell. 2013. PMID: 23845443 Free PMC article.
Differential IRAK signaling in hematologic malignancies.
Rhyasen GW, Bolanos L, Starczynowski DT. Rhyasen GW, et al. Among authors: starczynowski dt. Exp Hematol. 2013 Dec;41(12):1005-7. doi: 10.1016/j.exphem.2013.09.008. Epub 2013 Sep 29. Exp Hematol. 2013. PMID: 24084080 Free PMC article. No abstract available.
An MDS xenograft model utilizing a patient-derived cell line.
Rhyasen GW, Wunderlich M, Tohyama K, Garcia-Manero G, Mulloy JC, Starczynowski DT. Rhyasen GW, et al. Among authors: starczynowski dt. Leukemia. 2014 May;28(5):1142-5. doi: 10.1038/leu.2013.372. Epub 2013 Dec 11. Leukemia. 2014. PMID: 24326684 Free PMC article. No abstract available.
Myeloid malignancies with chromosome 5q deletions acquire a dependency on an intrachromosomal NF-κB gene network.
Fang J, Barker B, Bolanos L, Liu X, Jerez A, Makishima H, Christie S, Chen X, Rao DS, Grimes HL, Komurov K, Weirauch MT, Cancelas JA, Maciejewski JP, Starczynowski DT. Fang J, et al. Among authors: starczynowski dt. Cell Rep. 2014 Sep 11;8(5):1328-38. doi: 10.1016/j.celrep.2014.07.062. Epub 2014 Sep 4. Cell Rep. 2014. PMID: 25199827 Free PMC article.
Deconstructing innate immune signaling in myelodysplastic syndromes.
Varney ME, Melgar K, Niederkorn M, Smith M, Barreyro L, Starczynowski DT. Varney ME, et al. Among authors: starczynowski dt. Exp Hematol. 2015 Aug;43(8):587-598. doi: 10.1016/j.exphem.2015.05.016. Epub 2015 Jul 2. Exp Hematol. 2015. PMID: 26143580 Free PMC article. Review.
TRAF6 Mediates Basal Activation of NF-κB Necessary for Hematopoietic Stem Cell Homeostasis.
Fang J, Muto T, Kleppe M, Bolanos LC, Hueneman KM, Walker CS, Sampson L, Wellendorf AM, Chetal K, Choi K, Salomonis N, Choi Y, Zheng Y, Cancelas JA, Levine RL, Starczynowski DT. Fang J, et al. Among authors: starczynowski dt. Cell Rep. 2018 Jan 30;22(5):1250-1262. doi: 10.1016/j.celrep.2018.01.013. Cell Rep. 2018. PMID: 29386112 Free PMC article.
93 results