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PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status.
Roodakker KR, Elsir T, Edqvist PD, Hägerstrand D, Carlson J, Lysiak M, Henriksson R, Pontén F, Rosell J, Söderkvist P, Stupp R, Tchougounova E, Nistér M, Malmström A, Smits A. Roodakker KR, et al. Among authors: ponten f. Oncotarget. 2016 Nov 8;7(45):72431-72442. doi: 10.18632/oncotarget.11957. Oncotarget. 2016. PMID: 27626492 Free PMC article.
Biomarker discovery in non-small cell lung cancer: integrating gene expression profiling, meta-analysis, and tissue microarray validation.
Botling J, Edlund K, Lohr M, Hellwig B, Holmberg L, Lambe M, Berglund A, Ekman S, Bergqvist M, Pontén F, König A, Fernandes O, Karlsson M, Helenius G, Karlsson C, Rahnenführer J, Hengstler JG, Micke P. Botling J, et al. Among authors: ponten f. Clin Cancer Res. 2013 Jan 1;19(1):194-204. doi: 10.1158/1078-0432.CCR-12-1139. Epub 2012 Oct 2. Clin Cancer Res. 2013. PMID: 23032747
Proximity Ligation Assay as a Tool for Antibody Validation in Human Tissues.
Lindskog C, Backman M, Zieba A, Asplund A, Uhlén M, Landegren U, Pontén F. Lindskog C, et al. Among authors: ponten f. J Histochem Cytochem. 2020 Jul;68(7):515-529. doi: 10.1369/0022155420936384. Epub 2020 Jun 30. J Histochem Cytochem. 2020. PMID: 32602410 Free PMC article.
A gene-centric approach to biomarker discovery identifies transglutaminase 1 as an epidermal autoantigen.
Landegren N, Ishii N, Aranda-Guillén M, Gunnarsson HI, Sardh F, Hallgren Å, Ståhle M, Hagforsen E, Bradley M, Edqvist PD, Pontén F, Mäkitie O, Eidsmo L, Norlén L, Achour A, Dahlbom I, Korponay-Szabó I, Agardh D, Alimohammadi M, Eriksson D, Hashimoto T, Kämpe O. Landegren N, et al. Among authors: ponten f. Proc Natl Acad Sci U S A. 2021 Dec 21;118(51):e2100687118. doi: 10.1073/pnas.2100687118. Proc Natl Acad Sci U S A. 2021. PMID: 34911754 Free PMC article.
CD99 is a novel prognostic stromal marker in non-small cell lung cancer.
Edlund K, Lindskog C, Saito A, Berglund A, Pontén F, Göransson-Kultima H, Isaksson A, Jirström K, Planck M, Johansson L, Lambe M, Holmberg L, Nyberg F, Ekman S, Bergqvist M, Landelius P, Lamberg K, Botling J, Ostman A, Micke P. Edlund K, et al. Among authors: ponten f. Int J Cancer. 2012 Nov 15;131(10):2264-73. doi: 10.1002/ijc.27518. Epub 2012 Apr 24. Int J Cancer. 2012. PMID: 22392539 Free article.
Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization.
Dieterich LC, Mellberg S, Langenkamp E, Zhang L, Zieba A, Salomäki H, Teichert M, Huang H, Edqvist PH, Kraus T, Augustin HG, Olofsson T, Larsson E, Söderberg O, Molema G, Pontén F, Georgii-Hemming P, Alafuzoff I, Dimberg A. Dieterich LC, et al. Among authors: ponten f. J Pathol. 2012 Nov;228(3):378-90. doi: 10.1002/path.4072. Epub 2012 Aug 31. J Pathol. 2012. PMID: 22786655
308 results