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Early detection of diabetic kidney disease by urinary proteomics and subsequent intervention with spironolactone to delay progression (PRIORITY): a prospective observational study and embedded randomised placebo-controlled trial.
Tofte N, Lindhardt M, Adamova K, Bakker SJL, Beige J, Beulens JWJ, Birkenfeld AL, Currie G, Delles C, Dimos I, Francová L, Frimodt-Møller M, Girman P, Göke R, Havrdova T, Heerspink HJL, Kooy A, Laverman GD, Mischak H, Navis G, Nijpels G, Noutsou M, Ortiz A, Parvanova A, Persson F, Petrie JR, Ruggenenti PL, Rutters F, Rychlík I, Siwy J, Spasovski G, Speeckaert M, Trillini M, Zürbig P, von der Leyen H, Rossing P; PRIORITY investigators. Tofte N, et al. Among authors: rychlik i. Lancet Diabetes Endocrinol. 2020 Apr;8(4):301-312. doi: 10.1016/S2213-8587(20)30026-7. Epub 2020 Mar 2. Lancet Diabetes Endocrinol. 2020. PMID: 32135136 Free article. Clinical Trial.
Urinary collagen fragments are significantly altered in diabetes: a link to pathophysiology.
Maahs DM, Siwy J, Argilés A, Cerna M, Delles C, Dominiczak AF, Gayrard N, Iphöfer A, Jänsch L, Jerums G, Medek K, Mischak H, Navis GJ, Roob JM, Rossing K, Rossing P, Rychlík I, Schiffer E, Schmieder RE, Wascher TC, Winklhofer-Roob BM, Zimmerli LU, Zürbig P, Snell-Bergeon JK. Maahs DM, et al. Among authors: rychlik i. PLoS One. 2010 Sep 28;5(9):e13051. doi: 10.1371/journal.pone.0013051. PLoS One. 2010. PMID: 20927192 Free PMC article.
Multicentric validation of proteomic biomarkers in urine specific for diabetic nephropathy.
Alkhalaf A, Zürbig P, Bakker SJ, Bilo HJ, Cerna M, Fischer C, Fuchs S, Janssen B, Medek K, Mischak H, Roob JM, Rossing K, Rossing P, Rychlík I, Sourij H, Tiran B, Winklhofer-Roob BM, Navis GJ; PREDICTIONS Group. Alkhalaf A, et al. Among authors: rychlik i. PLoS One. 2010 Oct 20;5(10):e13421. doi: 10.1371/journal.pone.0013421. PLoS One. 2010. PMID: 20975990 Free PMC article.
Atrasentan and renal events in patients with type 2 diabetes and chronic kidney disease (SONAR): a double-blind, randomised, placebo-controlled trial.
Heerspink HJL, Parving HH, Andress DL, Bakris G, Correa-Rotter R, Hou FF, Kitzman DW, Kohan D, Makino H, McMurray JJV, Melnick JZ, Miller MG, Pergola PE, Perkovic V, Tobe S, Yi T, Wigderson M, de Zeeuw D; SONAR Committees and Investigators. Heerspink HJL, et al. Lancet. 2019 May 11;393(10184):1937-1947. doi: 10.1016/S0140-6736(19)30772-X. Epub 2019 Apr 14. Lancet. 2019. PMID: 30995972 Clinical Trial.
Polymorphisms in the vitamin D receptor gene and parathyroid hormone gene in the development and progression of diabetes mellitus and its chronic complications, diabetic nephropathy and non-diabetic renal disease.
Vedralová M, Kotrbova-Kozak A, Zelezníková V, Zoubková H, Rychlík I, Cerná M. Vedralová M, et al. Among authors: rychlik i. Kidney Blood Press Res. 2012;36(1):1-9. doi: 10.1159/000339021. Epub 2012 Jun 18. Kidney Blood Press Res. 2012. PMID: 22777106 Free article.
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy.
Perkovic V, Jardine MJ, Neal B, Bompoint S, Heerspink HJL, Charytan DM, Edwards R, Agarwal R, Bakris G, Bull S, Cannon CP, Capuano G, Chu PL, de Zeeuw D, Greene T, Levin A, Pollock C, Wheeler DC, Yavin Y, Zhang H, Zinman B, Meininger G, Brenner BM, Mahaffey KW; CREDENCE Trial Investigators. Perkovic V, et al. N Engl J Med. 2019 Jun 13;380(24):2295-2306. doi: 10.1056/NEJMoa1811744. Epub 2019 Apr 14. N Engl J Med. 2019. PMID: 30990260 Free article. Clinical Trial.
The nephrology crystal ball: the medium-term future.
Zoccali C, Blankestijn PJ, Bruchfeld A, Capasso G, Fliser D, Fouque D, Goumenos D, Massy Z, Rychlık I, Soler MJ, Stevens K, Spasovski G, Wanner C. Zoccali C, et al. Among authors: rychlik i. Nephrol Dial Transplant. 2020 Feb 1;35(2):222-226. doi: 10.1093/ndt/gfz199. Nephrol Dial Transplant. 2020. PMID: 31598700
Funding kidney research as a public health priority: challenges and opportunities.
Zoccali C, Vanholder R, Wagner CA, Anders HJ, Blankestijn PJ, Bruchfeld A, Capasso G, Cozzolino M, Dekker FW, Fliser D, Fouque D, Gansevoort RT, Goumenos D, Jager KJ, Massy ZA, Oostrom TAJ, Rychlık I, Soler MJ, Stevens K, Spasovski G, Wanner C. Zoccali C, et al. Among authors: rychlik i. Nephrol Dial Transplant. 2021 Dec 31;37(1):21-28. doi: 10.1093/ndt/gfaa163. Nephrol Dial Transplant. 2021. PMID: 32888017
413 results