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Pharmacological Characterization of the Novel and Selective α7 Nicotinic Acetylcholine Receptor-Positive Allosteric Modulator BNC375.
Wang X, Daley C, Gakhar V, Lange HS, Vardigan JD, Pearson M, Zhou X, Warren L, Miller CO, Belden M, Harvey AJ, Grishin AA, Coles CJ, O'Connor SM, Thomson F, Duffy JL, Bell IM, Uslaner JM. Wang X, et al. Among authors: grishin aa. J Pharmacol Exp Ther. 2020 May;373(2):311-324. doi: 10.1124/jpet.119.263483. Epub 2020 Feb 24. J Pharmacol Exp Ther. 2020. PMID: 32094294
Discovery of BNC375, a Potent, Selective, and Orally Available Type I Positive Allosteric Modulator of α7 nAChRs.
Harvey AJ, Avery TD, Schaeffer L, Joseph C, Huff BC, Singh R, Morice C, Giethlen B, Grishin AA, Coles CJ, Kolesik P, Wagner S, Andriambeloson E, Huyard B, Poiraud E, Paul D, O'Connor SM. Harvey AJ, et al. Among authors: grishin aa. ACS Med Chem Lett. 2019 Mar 25;10(5):754-760. doi: 10.1021/acsmedchemlett.9b00001. eCollection 2019 May 9. ACS Med Chem Lett. 2019. PMID: 31097995 Free PMC article.
Structure-activity relationship studies of SEN12333 analogues: determination of the optimal requirements for binding affinities at α7 nAChRs through incorporation of known structural motifs.
Beinat C, Reekie T, Banister SD, O'Brien-Brown J, Xie T, Olson TT, Xiao Y, Harvey A, O'Connor S, Coles C, Grishin A, Kolesik P, Tsanaktsidis J, Kassiou M. Beinat C, et al. Eur J Med Chem. 2015 May 5;95:277-301. doi: 10.1016/j.ejmech.2015.03.025. Epub 2015 Mar 14. Eur J Med Chem. 2015. PMID: 25827398
Solving the alpha-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists.
Muttenthaler M, Nevin ST, Grishin AA, Ngo ST, Choy PT, Daly NL, Hu SH, Armishaw CJ, Wang CI, Lewis RJ, Martin JL, Noakes PG, Craik DJ, Adams DJ, Alewood PF. Muttenthaler M, et al. Among authors: grishin aa. J Am Chem Soc. 2010 Mar 17;132(10):3514-22. doi: 10.1021/ja910602h. J Am Chem Soc. 2010. PMID: 20163143
A New Technology for Recovery of Locomotion in Patients after a Stroke.
Moshonkina TR, Zharova EN, Ananev SS, Shandybina ND, Vershinina EA, Lyakhovetskii VA, Grishin AA, Shlyakhto EV, Gerasimenko YP. Moshonkina TR, et al. Among authors: grishin aa. Dokl Biochem Biophys. 2022 Dec;507(1):353-356. doi: 10.1134/S1607672922340087. Epub 2023 Feb 14. Dokl Biochem Biophys. 2022. PMID: 36787001
Dependence of Brain-Computer Interface Control Training on Personality Traits.
Bobrova EV, Reshetnikova VV, Vershinina EA, Grishin AA, Isaev MR, Bobrov PD, Gerasimenko YP. Bobrova EV, et al. Among authors: grishin aa. Dokl Biochem Biophys. 2022 Dec;507(1):273-277. doi: 10.1134/S1607672922060035. Epub 2023 Feb 14. Dokl Biochem Biophys. 2022. PMID: 36786985
44 results