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The mouse HP1 proteins are essential for preventing liver tumorigenesis.
Saksouk N, Hajdari S, Perez Y, Pratlong M, Barrachina C, Graber C, Grégoire D, Zavoriti A, Sarrazin A, Pirot N, Noël JY, Khellaf L, Fabbrizio E, Julien E, Cammas FM. Saksouk N, et al. Among authors: cammas fm. Oncogene. 2020 Mar;39(13):2676-2691. doi: 10.1038/s41388-020-1177-8. Epub 2020 Feb 4. Oncogene. 2020. PMID: 32020053
Critical role for TRIM28 and HP1β/γ in the epigenetic control of T cell metabolic reprograming and effector differentiation.
Gehrmann U, Burbage M, Zueva E, Goudot C, Esnault C, Ye M, Carpier JM, Burgdorf N, Hoyler T, Suarez G, Joannas L, Heurtebise-Chrétien S, Durand S, Panes R, Bellemare-Pelletier A, Sáez PJ, Aprahamian F, Lefevre D, Adoue V, Zine El Aabidine A, Muhammad Ahmad M, Hivroz C, Joffre O, Cammas F, Kroemer G, Gagnon E, Andrau JC, Amigorena S. Gehrmann U, et al. Among authors: cammas f. Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25839-25849. doi: 10.1073/pnas.1901639116. Epub 2019 Nov 27. Proc Natl Acad Sci U S A. 2019. PMID: 31776254 Free PMC article.
Disruption of the interaction between transcriptional intermediary factor 1{beta} and heterochromatin protein 1 leads to a switch from DNA hyper- to hypomethylation and H3K9 to H3K27 trimethylation on the MEST promoter correlating with gene reactivation.
Riclet R, Chendeb M, Vonesch JL, Koczan D, Thiesen HJ, Losson R, Cammas F. Riclet R, et al. Among authors: cammas f. Mol Biol Cell. 2009 Jan;20(1):296-305. doi: 10.1091/mbc.e08-05-0510. Epub 2008 Oct 15. Mol Biol Cell. 2009. PMID: 18923144 Free PMC article.
35 results