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Selective inhibition of Ph-positive ALL cell growth through kinase-dependent and -independent effects by CDK6-specific PROTACs.
De Dominici M, Porazzi P, Xiao Y, Chao A, Tang HY, Kumar G, Fortina P, Spinelli O, Rambaldi A, Peterson LF, Petruk S, Barletta C, Mazo A, Cingolani G, Salvino JM, Calabretta B. De Dominici M, et al. Among authors: cingolani g. Blood. 2020 Apr 30;135(18):1560-1573. doi: 10.1182/blood.2019003604. Blood. 2020. PMID: 32040545 Free PMC article.
Structure-Based Screen Identifies a Potent Small Molecule Inhibitor of Stat5a/b with Therapeutic Potential for Prostate Cancer and Chronic Myeloid Leukemia.
Liao Z, Gu L, Vergalli J, Mariani SA, De Dominici M, Lokareddy RK, Dagvadorj A, Purushottamachar P, McCue PA, Trabulsi E, Lallas CD, Gupta S, Ellsworth E, Blackmon S, Ertel A, Fortina P, Leiby B, Xia G, Rui H, Hoang DT, Gomella LG, Cingolani G, Njar V, Pattabiraman N, Calabretta B, Nevalainen MT. Liao Z, et al. Among authors: cingolani g. Mol Cancer Ther. 2015 Aug;14(8):1777-93. doi: 10.1158/1535-7163.MCT-14-0883. Epub 2015 May 29. Mol Cancer Ther. 2015. PMID: 26026053 Free PMC article.
RNA Recognition-like Motifs Activate a Mitogen-Activated Protein Kinase.
Phillips T, Tio CW, Omerza G, Rimal A, Lokareddy RK, Cingolani G, Winter E. Phillips T, et al. Among authors: cingolani g. Biochemistry. 2018 Dec 18;57(50):6878-6887. doi: 10.1021/acs.biochem.8b01032. Epub 2018 Dec 4. Biochemistry. 2018. PMID: 30452242 Free PMC article.
134 results