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Activation of liver X receptors inhibits experimental fibrosis by interfering with interleukin-6 release from macrophages.
Beyer C, Huang J, Beer J, Zhang Y, Palumbo-Zerr K, Zerr P, Distler A, Dees C, Maier C, Munoz L, Krönke G, Uderhardt S, Distler O, Jones S, Rose-John S, Oravecz T, Schett G, Distler JH. Beyer C, et al. Among authors: zhang y. Ann Rheum Dis. 2015 Jun;74(6):1317-24. doi: 10.1136/annrheumdis-2013-204401. Epub 2014 Mar 11. Ann Rheum Dis. 2015. PMID: 24618263
The transcription factor GLI2 as a downstream mediator of transforming growth factor-β-induced fibroblast activation in SSc.
Liang R, Šumová B, Cordazzo C, Mallano T, Zhang Y, Wohlfahrt T, Dees C, Ramming A, Krasowska D, Michalska-Jakubus M, Distler O, Schett G, Šenolt L, Distler JH. Liang R, et al. Among authors: zhang y. Ann Rheum Dis. 2017 Apr;76(4):756-764. doi: 10.1136/annrheumdis-2016-209698. Epub 2016 Oct 28. Ann Rheum Dis. 2017. PMID: 27793816
The histone demethylase Jumonji domain-containing protein 3 (JMJD3) regulates fibroblast activation in systemic sclerosis.
Bergmann C, Brandt A, Merlevede B, Hallenberger L, Dees C, Wohlfahrt T, Pötter S, Zhang Y, Chen CW, Mallano T, Liang R, Kagwiria R, Kreuter A, Pantelaki I, Bozec A, Abraham D, Rieker R, Ramming A, Distler O, Schett G, Distler JHW. Bergmann C, et al. Among authors: zhang y. Ann Rheum Dis. 2018 Jan;77(1):150-158. doi: 10.1136/annrheumdis-2017-211501. Epub 2017 Oct 25. Ann Rheum Dis. 2018. PMID: 29070530
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