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Prion protein glycans reduce intracerebral fibril formation and spongiosis in prion disease.
Sevillano AM, Aguilar-Calvo P, Kurt TD, Lawrence JA, Soldau K, Nam TH, Schumann T, Pizzo DP, Nyström S, Choudhury B, Altmeppen H, Esko JD, Glatzel M, Nilsson KPR, Sigurdson CJ. Sevillano AM, et al. Among authors: sigurdson cj. J Clin Invest. 2020 Mar 2;130(3):1350-1362. doi: 10.1172/JCI131564. J Clin Invest. 2020. PMID: 31985492 Free PMC article.
Strain fidelity of chronic wasting disease upon murine adaptation.
Sigurdson CJ, Manco G, Schwarz P, Liberski P, Hoover EA, Hornemann S, Polymenidou M, Miller MW, Glatzel M, Aguzzi A. Sigurdson CJ, et al. J Virol. 2006 Dec;80(24):12303-11. doi: 10.1128/JVI.01120-06. Epub 2006 Oct 4. J Virol. 2006. PMID: 17020952 Free PMC article.
Prion strain discrimination using luminescent conjugated polymers.
Sigurdson CJ, Nilsson KP, Hornemann S, Manco G, Polymenidou M, Schwarz P, Leclerc M, Hammarström P, Wüthrich K, Aguzzi A. Sigurdson CJ, et al. Nat Methods. 2007 Dec;4(12):1023-30. doi: 10.1038/nmeth1131. Epub 2007 Nov 18. Nat Methods. 2007. PMID: 18026110
De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis.
Sigurdson CJ, Nilsson KP, Hornemann S, Heikenwalder M, Manco G, Schwarz P, Ott D, Rülicke T, Liberski PP, Julius C, Falsig J, Stitz L, Wüthrich K, Aguzzi A. Sigurdson CJ, et al. Proc Natl Acad Sci U S A. 2009 Jan 6;106(1):304-9. doi: 10.1073/pnas.0810680105. Epub 2008 Dec 10. Proc Natl Acad Sci U S A. 2009. PMID: 19073920 Free PMC article.
Novel pentameric thiophene derivatives for in vitro and in vivo optical imaging of a plethora of protein aggregates in cerebral amyloidoses.
Aslund A, Sigurdson CJ, Klingstedt T, Grathwohl S, Bolmont T, Dickstein DL, Glimsdal E, Prokop S, Lindgren M, Konradsson P, Holtzman DM, Hof PR, Heppner FL, Gandy S, Jucker M, Aguzzi A, Hammarström P, Nilsson KP. Aslund A, et al. Among authors: sigurdson cj. ACS Chem Biol. 2009 Aug 21;4(8):673-84. doi: 10.1021/cb900112v. ACS Chem Biol. 2009. PMID: 19624097 Free PMC article.
A molecular switch controls interspecies prion disease transmission in mice.
Sigurdson CJ, Nilsson KP, Hornemann S, Manco G, Fernández-Borges N, Schwarz P, Castilla J, Wüthrich K, Aguzzi A. Sigurdson CJ, et al. J Clin Invest. 2010 Jul;120(7):2590-9. doi: 10.1172/JCI42051. Epub 2010 Jun 14. J Clin Invest. 2010. PMID: 20551516 Free PMC article.
Prion strain interactions are highly selective.
Nilsson KP, Joshi-Barr S, Winson O, Sigurdson CJ. Nilsson KP, et al. Among authors: sigurdson cj. J Neurosci. 2010 Sep 8;30(36):12094-102. doi: 10.1523/JNEUROSCI.2417-10.2010. J Neurosci. 2010. PMID: 20826672 Free PMC article.
Tracking protein aggregate interactions.
Sigurdson CJ, Bartz JC, Nilsson KP. Sigurdson CJ, et al. Prion. 2011 Apr-Jun;5(2):52-5. doi: 10.4161/pri.5.2.16173. Epub 2011 Apr 1. Prion. 2011. PMID: 21597336 Free PMC article. Review.
Structure of the β2-α2 loop and interspecies prion transmission.
Bett C, Fernández-Borges N, Kurt TD, Lucero M, Nilsson KP, Castilla J, Sigurdson CJ. Bett C, et al. Among authors: sigurdson cj. FASEB J. 2012 Jul;26(7):2868-76. doi: 10.1096/fj.11-200923. Epub 2012 Apr 9. FASEB J. 2012. PMID: 22490928 Free PMC article.
81 results