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Structural instability and divergence from conserved residues underlie intracellular retention of mammalian odorant receptors.
Proc Natl Acad Sci U S A. 2020 Feb 11;117(6):2957-2967. doi: 10.1073/pnas.1915520117. Epub 2020 Jan 23.
Proc Natl Acad Sci U S A. 2020.
PMID: 31974307
Free PMC article.
Odorant Receptor 7D4 Activation Dynamics.
de March CA, Topin J, Bruguera E, Novikov G, Ikegami K, Matsunami H, Golebiowski J.
de March CA, et al.
Angew Chem Int Ed Engl. 2018 Apr 16;57(17):4554-4558. doi: 10.1002/anie.201713065. Epub 2018 Mar 24.
Angew Chem Int Ed Engl. 2018.
PMID: 29462498
Free PMC article.
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Global Survey of Variation in a Human Olfactory Receptor Gene Reveals Signatures of Non-Neutral Evolution.
Hoover KC, Gokcumen O, Qureshy Z, Bruguera E, Savangsuksa A, Cobb M, Matsunami H.
Hoover KC, et al.
Chem Senses. 2015 Sep;40(7):481-8. doi: 10.1093/chemse/bjv030. Epub 2015 Jun 13.
Chem Senses. 2015.
PMID: 26072518
Free PMC article.
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The co-receptor Tspan12 directly captures Norrin to promote ligand-specific β-catenin signaling.
Bruguera ES, Mahoney JP, Weis WI.
Bruguera ES, et al.
bioRxiv [Preprint]. 2024 Feb 3:2024.02.03.578714. doi: 10.1101/2024.02.03.578714.
bioRxiv. 2024.
PMID: 38352533
Free PMC article.
Preprint.
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PI(4,5)P2-stimulated positive feedback drives the recruitment of Dishevelled to Frizzled in Wnt-β-catenin signaling.
Mahoney JP, Bruguera ES, Vasishtha M, Killingsworth LB, Kyaw S, Weis WI.
Mahoney JP, et al. Among authors: bruguera es.
Sci Signal. 2022 Aug 23;15(748):eabo2820. doi: 10.1126/scisignal.abo2820. Epub 2022 Aug 23.
Sci Signal. 2022.
PMID: 35998232
Free PMC article.
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Reconstitution of purified membrane protein dimers in lipid nanodiscs with defined stoichiometry and orientation using a split GFP tether.
Bruguera ES, Mahoney JP, Weis WI.
Bruguera ES, et al.
J Biol Chem. 2022 Apr;298(4):101628. doi: 10.1016/j.jbc.2022.101628. Epub 2022 Jan 22.
J Biol Chem. 2022.
PMID: 35074428
Free PMC article.
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