Doktor TK - Search Results

1

Tissue-resident macrophages in omentum promote metastatic spread of ovarian cancer.

Etzerodt A, Moulin M, Doktor TK, Delfini M, Mossadegh-Keller N, Bajenoff M, Sieweke MH, Moestrup SK, Auphan-Anezin N, Lawrence T. Etzerodt A, et al. Among authors: doktor tk. J Exp Med. 2020 Apr 6;217(4):e20191869. doi: 10.1084/jem.20191869. J Exp Med. 2020. PMID: 31951251 Free PMC article.

2

Down-regulation of CK2α correlates with decreased expression levels of DNA replication minichromosome maintenance protein complex (MCM) genes.

Schaefer S, Doktor TK, Frederiksen SB, Chea K, Hlavacova M, Bruun GH, Rabjerg M, Andresen BS, Dominguez I, Guerra B. Schaefer S, et al. Among authors: doktor tk. Sci Rep. 2019 Oct 10;9(1):14581. doi: 10.1038/s41598-019-51056-5. Sci Rep. 2019. PMID: 31601942 Free PMC article.

3

Genome-wide epigenetic and mRNA-expression profiling followed by CRISPR/Cas9-mediated gene-disruptions corroborate the MIR141/MIR200C-ZEB1/ZEB2-FGFR1 axis in acquired EMT-associated EGFR TKI-resistance in NSCLC cells.

Vad-Nielsen J, Staunstrup NH, Kjeldsen ML, Dybdal N, Flandin G, De Stradis C, Daugaard TF, Vilsbøll-Larsen T, Maansson CT, Doktor TK, Sorensen BS, Nielsen AL. Vad-Nielsen J, et al. Among authors: doktor tk. Transl Lung Cancer Res. 2023 Jan 31;12(1):42-65. doi: 10.21037/tlcr-22-507. Epub 2023 Jan 13. Transl Lung Cancer Res. 2023. PMID: 36762066 Free PMC article.

4

The phenylalanine hydroxylase c.30C>G synonymous variation (p.G10G) creates a common exonic splicing silencer.

Dobrowolski SF, Andersen HS, Doktor TK, Andresen BS. Dobrowolski SF, et al. Among authors: doktor tk. Mol Genet Metab. 2010 Aug;100(4):316-23. doi: 10.1016/j.ymgme.2010.04.002. Epub 2010 Apr 14. Mol Genet Metab. 2010. PMID: 20457534

5

SMN2 exon 7 splicing is inhibited by binding of hnRNP A1 to a common ESS motif that spans the 3' splice site.

Doktor TK, Schroeder LD, Vested A, Palmfeldt J, Andersen HS, Gregersen N, Andresen BS. Doktor TK, et al. Hum Mutat. 2011 Feb;32(2):220-30. doi: 10.1002/humu.21419. Epub 2011 Jan 25. Hum Mutat. 2011. PMID: 21120954

6

CUGBP1 and MBNL1 preferentially bind to 3' UTRs and facilitate mRNA decay.

Masuda A, Andersen HS, Doktor TK, Okamoto T, Ito M, Andresen BS, Ohno K. Masuda A, et al. Among authors: doktor tk. Sci Rep. 2012;2:209. doi: 10.1038/srep00209. Epub 2012 Jan 4. Sci Rep. 2012. PMID: 22355723 Free PMC article.

7

A synonymous polymorphic variation in ACADM exon 11 affects splicing efficiency and may affect fatty acid oxidation.

Bruun GH, Doktor TK, Andresen BS. Bruun GH, et al. Among authors: doktor tk. Mol Genet Metab. 2013 Sep-Oct;110(1-2):122-8. doi: 10.1016/j.ymgme.2013.06.005. Epub 2013 Jun 12. Mol Genet Metab. 2013. PMID: 23810226

8

The ETFDH c.158A>G variation disrupts the balanced interplay of ESE- and ESS-binding proteins thereby causing missplicing and multiple Acyl-CoA dehydrogenation deficiency.

Olsen RK, Brøner S, Sabaratnam R, Doktor TK, Andersen HS, Bruun GH, Gahrn B, Stenbroen V, Olpin SE, Dobbie A, Gregersen N, Andresen BS. Olsen RK, et al. Among authors: doktor tk. Hum Mutat. 2014 Jan;35(1):86-95. doi: 10.1002/humu.22455. Epub 2013 Oct 28. Hum Mutat. 2014. PMID: 24123825

9

Absence of an intron splicing silencer in porcine Smn1 intron 7 confers immunity to the exon skipping mutation in human SMN2.

Doktor TK, Schrøder LD, Andersen HS, Brøner S, Kitewska A, Sørensen CB, Andresen BS. Doktor TK, et al. PLoS One. 2014 Jun 3;9(6):e98841. doi: 10.1371/journal.pone.0098841. eCollection 2014. PLoS One. 2014. PMID: 24892836 Free PMC article.

10

Splice-shifting oligonucleotide (SSO) mediated blocking of an exonic splicing enhancer (ESE) created by the prevalent c.903+469T>C MTRR mutation corrects splicing and restores enzyme activity in patient cells.

Palhais B, Præstegaard VS, Sabaratnam R, Doktor TK, Lutz S, Burda P, Suormala T, Baumgartner M, Fowler B, Bruun GH, Andersen HS, Kožich V, Andresen BS. Palhais B, et al. Among authors: doktor tk. Nucleic Acids Res. 2015 May 19;43(9):4627-39. doi: 10.1093/nar/gkv275. Epub 2015 Apr 15. Nucleic Acids Res. 2015. PMID: 25878036 Free PMC article.

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