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Inhibition of Histone H3K27 Demethylases Inactivates Brachyury (TBXT) and Promotes Chordoma Cell Death.
Cottone L, Cribbs AP, Khandelwal G, Wells G, Ligammari L, Philpott M, Tumber A, Lombard P, Hookway ES, Szommer T, Johansson C, Brennan PE, Pillay N, Jenner RG, Oppermann U, Flanagan AM. Cottone L, et al. Among authors: ligammari l. Cancer Res. 2020 Oct 15;80(20):4540-4551. doi: 10.1158/0008-5472.CAN-20-1387. Epub 2020 Aug 27. Cancer Res. 2020. PMID: 32855205
Optimizing CRISPR/Cas9 Editing of Repetitive Single Nucleotide Variants.
Usher I, Ligammari L, Ahrabi S, Hepburn E, Connolly C, Bond GL, Flanagan AM, Cottone L. Usher I, et al. Among authors: ligammari l. Front Genome Ed. 2022 Jul 5;4:932434. doi: 10.3389/fgeed.2022.932434. eCollection 2022. Front Genome Ed. 2022. PMID: 35865001 Free PMC article.
Aberrant paracrine signalling for bone remodelling underlies the mutant histone-driven giant cell tumour of bone.
Cottone L, Ligammari L, Lee HM, Knowles HJ, Henderson S, Bianco S, Davies C, Strauss S, Amary F, Leite AP, Tirabosco R, Haendler K, Schultze JL, Herrero J, O'Donnell P, Grigoriadis AE, Salomoni P, Flanagan AM. Cottone L, et al. Among authors: ligammari l. Cell Death Differ. 2022 Dec;29(12):2459-2471. doi: 10.1038/s41418-022-01031-x. Epub 2022 Aug 3. Cell Death Differ. 2022. PMID: 36138226 Free PMC article.
Repo-Man/PP1 regulates heterochromatin formation in interphase.
de Castro IJ, Budzak J, Di Giacinto ML, Ligammari L, Gokhan E, Spanos C, Moralli D, Richardson C, de Las Heras JI, Salatino S, Schirmer EC, Ullman KS, Bickmore WA, Green C, Rappsilber J, Lamble S, Goldberg MW, Vinciotti V, Vagnarelli P. de Castro IJ, et al. Among authors: ligammari l. Nat Commun. 2017 Jan 16;8:14048. doi: 10.1038/ncomms14048. Nat Commun. 2017. PMID: 28091603 Free PMC article.