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A novel class of small molecule inhibitors with radioprotective properties.
Marek J, Tichy A, Havelek R, Seifrtova M, Filipova A, Andrejsova L, Kucera T, Prchal L, Muckova L, Rezacova M, Sinkorova Z, Pejchal J. Marek J, et al. Among authors: kucera t. Eur J Med Chem. 2020 Feb 1;187:111606. doi: 10.1016/j.ejmech.2019.111606. Epub 2020 Jan 1. Eur J Med Chem. 2020. PMID: 31901334
Development of 2-Methoxyhuprine as Novel Lead for Alzheimer's Disease Therapy.
Mezeiova E, Korabecny J, Sepsova V, Hrabinova M, Jost P, Muckova L, Kucera T, Dolezal R, Misik J, Spilovska K, Pham NL, Pokrievkova L, Roh J, Jun D, Soukup O, Kaping D, Kuca K. Mezeiova E, et al. Among authors: kucera t. Molecules. 2017 Jul 28;22(8):1265. doi: 10.3390/molecules22081265. Molecules. 2017. PMID: 28788095 Free PMC article.
The concept of hybrid molecules of tacrine and benzyl quinolone carboxylic acid (BQCA) as multifunctional agents for Alzheimer's disease.
Hepnarova V, Korabecny J, Matouskova L, Jost P, Muckova L, Hrabinova M, Vykoukalova N, Kerhartova M, Kucera T, Dolezal R, Nepovimova E, Spilovska K, Mezeiova E, Pham NL, Jun D, Staud F, Kaping D, Kuca K, Soukup O. Hepnarova V, et al. Among authors: kucera t. Eur J Med Chem. 2018 Apr 25;150:292-306. doi: 10.1016/j.ejmech.2018.02.083. Epub 2018 Mar 2. Eur J Med Chem. 2018. PMID: 29533874
Comparative Study on the Application of Mesenchymal Stromal Cells Combined with Tricalcium Phosphate Scaffold into Femoral Bone Defects.
Šponer P, Kučera T, Brtková J, Urban K, Kočí Z, Měřička P, Bezrouk A, Konrádová Š, Filipová A, Filip S. Šponer P, et al. Among authors: kucera t. Cell Transplant. 2018 Oct;27(10):1459-1468. doi: 10.1177/0963689718794918. Epub 2018 Sep 11. Cell Transplant. 2018. PMID: 30203687 Free PMC article. Clinical Trial.
Derivatives of the β-Crinane Amaryllidaceae Alkaloid Haemanthamine as Multi-Target Directed Ligands for Alzheimer's Disease.
Kohelová E, Peřinová R, Maafi N, Korábečný J, Hulcová D, Maříková J, Kučera T, Martínez González L, Hrabinova M, Vorčáková K, Nováková L, De Simone A, Havelek R, Cahlíková L. Kohelová E, et al. Among authors: kucera t. Molecules. 2019 Apr 3;24(7):1307. doi: 10.3390/molecules24071307. Molecules. 2019. PMID: 30987121 Free PMC article.
Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase.
Karabanovich G, Dušek J, Savková K, Pavliš O, Pávková I, Korábečný J, Kučera T, Kočová Vlčková H, Huszár S, Konyariková Z, Konečná K, Jand'ourek O, Stolaříková J, Korduláková J, Vávrová K, Pávek P, Klimešová V, Hrabálek A, Mikušová K, Roh J. Karabanovich G, et al. Among authors: kucera t. J Med Chem. 2019 Sep 12;62(17):8115-8139. doi: 10.1021/acs.jmedchem.9b00912. Epub 2019 Aug 22. J Med Chem. 2019. PMID: 31393122
Substituted Piperazines as Novel Potential Radioprotective Agents.
Filipova A, Marek J, Havelek R, Pejchal J, Jelicova M, Cizkova J, Majorosova M, Muckova L, Kucera T, Prchal L, Psotka M, Zivna N, Koutova D, Sinkorova Z, Rezacova M, Tichy A. Filipova A, et al. Among authors: kucera t. Molecules. 2020 Jan 25;25(3):532. doi: 10.3390/molecules25030532. Molecules. 2020. PMID: 31991816 Free PMC article.
166 results