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VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease.
Kim J, Gupta R, Blanco LP, Yang S, Shteinfer-Kuzmine A, Wang K, Zhu J, Yoon HE, Wang X, Kerkhofs M, Kang H, Brown AL, Park SJ, Xu X, Zandee van Rilland E, Kim MK, Cohen JI, Kaplan MJ, Shoshan-Barmatz V, Chung JH. Kim J, et al. Among authors: kaplan mj. Science. 2019 Dec 20;366(6472):1531-1536. doi: 10.1126/science.aav4011. Epub 2019 Dec 19. Science. 2019. PMID: 31857488 Free PMC article.
Update on cardiovascular disease in lupus.
Lewandowski LB, Kaplan MJ. Lewandowski LB, et al. Among authors: kaplan mj. Curr Opin Rheumatol. 2016 Sep;28(5):468-76. doi: 10.1097/BOR.0000000000000307. Curr Opin Rheumatol. 2016. PMID: 27227346 Free PMC article. Review.
Tofacitinib Ameliorates Murine Lupus and Its Associated Vascular Dysfunction.
Furumoto Y, Smith CK, Blanco L, Zhao W, Brooks SR, Thacker SG, Abdalrahman Z, Sciumè G, Tsai WL, Trier AM, Nunez L, Mast L, Hoffmann V, Remaley AT, O'Shea JJ, Kaplan MJ, Gadina M. Furumoto Y, et al. Among authors: kaplan mj. Arthritis Rheumatol. 2017 Jan;69(1):148-160. doi: 10.1002/art.39818. Arthritis Rheumatol. 2017. PMID: 27429362 Free PMC article.
Metabolic abnormalities and oxidative stress in lupus.
Lightfoot YL, Blanco LP, Kaplan MJ. Lightfoot YL, et al. Among authors: kaplan mj. Curr Opin Rheumatol. 2017 Sep;29(5):442-449. doi: 10.1097/BOR.0000000000000413. Curr Opin Rheumatol. 2017. PMID: 28639951 Free PMC article. Review.
Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus.
Mistry P, Nakabo S, O'Neil L, Goel RR, Jiang K, Carmona-Rivera C, Gupta S, Chan DW, Carlucci PM, Wang X, Naz F, Manna Z, Dey A, Mehta NN, Hasni S, Dell'Orso S, Gutierrez-Cruz G, Sun HW, Kaplan MJ. Mistry P, et al. Among authors: kaplan mj. Proc Natl Acad Sci U S A. 2019 Dec 10;116(50):25222-25228. doi: 10.1073/pnas.1908576116. Epub 2019 Nov 21. Proc Natl Acad Sci U S A. 2019. PMID: 31754025 Free PMC article.
Interferon lambda promotes immune dysregulation and tissue inflammation in TLR7-induced lupus.
Goel RR, Wang X, O'Neil LJ, Nakabo S, Hasneen K, Gupta S, Wigerblad G, Blanco LP, Kopp JB, Morasso MI, Kotenko SV, Yu ZX, Carmona-Rivera C, Kaplan MJ. Goel RR, et al. Among authors: kaplan mj. Proc Natl Acad Sci U S A. 2020 Mar 10;117(10):5409-5419. doi: 10.1073/pnas.1916897117. Epub 2020 Feb 24. Proc Natl Acad Sci U S A. 2020. PMID: 32094169 Free PMC article.
383 results