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Comprehensive epigenome characterization reveals diverse transcriptional regulation across human vascular endothelial cells.
Nakato R, Wada Y, Nakaki R, Nagae G, Katou Y, Tsutsumi S, Nakajima N, Fukuhara H, Iguchi A, Kohro T, Kanki Y, Saito Y, Kobayashi M, Izumi-Taguchi A, Osato N, Tatsuno K, Kamio A, Hayashi-Takanaka Y, Wada H, Ohta S, Aikawa M, Nakajima H, Nakamura M, McGee RC, Heppner KW, Kawakatsu T, Genno M, Yanase H, Kume H, Senbonmatsu T, Homma Y, Nishimura S, Mitsuyama T, Aburatani H, Kimura H, Shirahige K. Nakato R, et al. Among authors: kobayashi m. Epigenetics Chromatin. 2019 Dec 19;12(1):77. doi: 10.1186/s13072-019-0319-0. Epigenetics Chromatin. 2019. PMID: 31856914 Free PMC article.
Lipid accumulation in smooth muscle cells under LDL loading is independent of LDL receptor pathway and enhanced by hypoxic conditions.
Wada Y, Sugiyama A, Yamamoto T, Naito M, Noguchi N, Yokoyama S, Tsujita M, Kawabe Y, Kobayashi M, Izumi A, Kohro T, Tanaka T, Taniguchi H, Koyama H, Hirano K, Yamashita S, Matsuzawa Y, Niki E, Hamakubo T, Kodama T. Wada Y, et al. Among authors: kobayashi m. Arterioscler Thromb Vasc Biol. 2002 Oct 1;22(10):1712-9. doi: 10.1161/01.atv.0000033834.57737.9b. Arterioscler Thromb Vasc Biol. 2002. PMID: 12377754
A wave of nascent transcription on activated human genes.
Wada Y, Ohta Y, Xu M, Tsutsumi S, Minami T, Inoue K, Komura D, Kitakami J, Oshida N, Papantonis A, Izumi A, Kobayashi M, Meguro H, Kanki Y, Mimura I, Yamamoto K, Mataki C, Hamakubo T, Shirahige K, Aburatani H, Kimura H, Kodama T, Cook PR, Ihara S. Wada Y, et al. Among authors: kobayashi m. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18357-61. doi: 10.1073/pnas.0902573106. Epub 2009 Oct 13. Proc Natl Acad Sci U S A. 2009. PMID: 19826084 Free PMC article.
Dynamic change of chromatin conformation in response to hypoxia enhances the expression of GLUT3 (SLC2A3) by cooperative interaction of hypoxia-inducible factor 1 and KDM3A.
Mimura I, Nangaku M, Kanki Y, Tsutsumi S, Inoue T, Kohro T, Yamamoto S, Fujita T, Shimamura T, Suehiro J, Taguchi A, Kobayashi M, Tanimura K, Inagaki T, Tanaka T, Hamakubo T, Sakai J, Aburatani H, Kodama T, Wada Y. Mimura I, et al. Among authors: kobayashi m. Mol Cell Biol. 2012 Aug;32(15):3018-32. doi: 10.1128/MCB.06643-11. Epub 2012 May 29. Mol Cell Biol. 2012. PMID: 22645302 Free PMC article.
Cross-enhancement of ANGPTL4 transcription by HIF1 alpha and PPAR beta/delta is the result of the conformational proximity of two response elements.
Inoue T, Kohro T, Tanaka T, Kanki Y, Li G, Poh HM, Mimura I, Kobayashi M, Taguchi A, Maejima T, Suehiro J, Sugiyama A, Kaneki K, Aruga H, Dong S, Stevens JF, Yamamoto S, Tsutsumi S, Fujita T, Ruan X, Aburatani H, Nangaku M, Ruan Y, Kodama T, Wada Y. Inoue T, et al. Among authors: kobayashi m. Genome Biol. 2014 Apr 10;15(4):R63. doi: 10.1186/gb-2014-15-4-r63. Genome Biol. 2014. PMID: 24721177 Free PMC article.
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