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Peptide vaccinations elicited strong immune responses that were reboosted by anti-PD1 therapy in a patient with myxofibrosarcoma.
Tsukahara T, Watanabe K, Murata K, Takahashi A, Mizushima E, Shibayama Y, Kameshima H, Hatae R, Ohno Y, Kawahara R, Murai A, Nakatsugawa M, Kubo T, Kanaseki T, Hirohashi Y, Terui T, Asanuma H, Hasegawa T, Sato N, Torigoe T. Tsukahara T, et al. Among authors: murai a. Cancer Immunol Immunother. 2020 Feb;69(2):189-197. doi: 10.1007/s00262-019-02455-0. Epub 2019 Dec 18. Cancer Immunol Immunother. 2020. PMID: 31853575 Free PMC article.
Case report: Long-term survival of a pancreatic cancer patient immunized with an SVN-2B peptide vaccine.
Shima H, Kutomi G, Satomi F, Imamura M, Kimura Y, Mizuguchi T, Watanabe K, Takahashi A, Murai A, Tsukahara T, Kanaseki T, Hirohashi Y, Iwayama Y, Tsuruma T, Kameshima H, Sato N, Torigoe T, Takemasa I. Shima H, et al. Among authors: murai a. Cancer Immunol Immunother. 2018 Oct;67(10):1603-1609. doi: 10.1007/s00262-018-2217-x. Epub 2018 Aug 1. Cancer Immunol Immunother. 2018. PMID: 30069687 Free PMC article.
Tumor-infiltrating CD8+ T cells recognize a heterogeneously expressed functional neoantigen in clear cell renal cell carcinoma.
Matsuki M, Hirohashi Y, Nakatsugawa M, Murai A, Kubo T, Hashimoto S, Tokita S, Murata K, Kanaseki T, Tsukahara T, Nishida S, Tanaka T, Kitamura H, Masumori N, Torigoe T. Matsuki M, et al. Among authors: murai a. Cancer Immunol Immunother. 2022 Apr;71(4):905-918. doi: 10.1007/s00262-021-03048-6. Epub 2021 Sep 7. Cancer Immunol Immunother. 2022. PMID: 34491407 Free PMC article.
Immunohistological analysis of pancreatic carcinoma after vaccination with survivin 2B peptide: Analysis of an autopsy series.
Kubo T, Tsurita G, Hirohashi Y, Yasui H, Ota Y, Watanabe K, Murai A, Matsuo K, Asanuma H, Shima H, Wada S, Nakatsugawa M, Kanaseki T, Tsukahara T, Mizuguchi T, Hirata K, Takemasa I, Imai K, Sato N, Torigoe T. Kubo T, et al. Among authors: murai a. Cancer Sci. 2019 Aug;110(8):2386-2395. doi: 10.1111/cas.14099. Epub 2019 Jul 11. Cancer Sci. 2019. PMID: 31206934 Free PMC article. Clinical Trial.
Randomized phase II trial of survivin 2B peptide vaccination for patients with HLA-A24-positive pancreatic adenocarcinoma.
Shima H, Tsurita G, Wada S, Hirohashi Y, Yasui H, Hayashi H, Miyakoshi T, Watanabe K, Murai A, Asanuma H, Tokita S, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Nakae Y, Sugita O, Ito YM, Ota Y, Kimura Y, Kutomi G, Hirata K, Mizuguchi T, Imai K, Takemasa I, Sato N, Torigoe T. Shima H, et al. Among authors: murai a. Cancer Sci. 2019 Aug;110(8):2378-2385. doi: 10.1111/cas.14106. Epub 2019 Jul 23. Cancer Sci. 2019. PMID: 31218770 Free PMC article. Clinical Trial.
GRIK2 is a target for bladder cancer stem-like cell-targeting immunotherapy.
Miyata H, Hirohashi Y, Yamada S, Yanagawa J, Murai A, Hashimoto S, Tokita S, Hori K, Abe T, Kubo T, Tsukahara T, Kanaseki T, Shinohara N, Torigoe T. Miyata H, et al. Among authors: murai a. Cancer Immunol Immunother. 2022 Apr;71(4):795-806. doi: 10.1007/s00262-021-03025-z. Epub 2021 Aug 18. Cancer Immunol Immunother. 2022. PMID: 34405274 Free PMC article.
Phosphorylation of HSF1 at serine 326 residue is related to the maintenance of gynecologic cancer stem cells through expression of HSP27.
Yasuda K, Hirohashi Y, Mariya T, Murai A, Tabuchi Y, Kuroda T, Kusumoto H, Takaya A, Yamamoto E, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Tamura Y, Hirano H, Hasegawa T, Saito T, Sato N, Torigoe T. Yasuda K, et al. Among authors: murai a. Oncotarget. 2017 May 9;8(19):31540-31553. doi: 10.18632/oncotarget.16361. Oncotarget. 2017. PMID: 28415561 Free PMC article.
Cellular stress induces cancer stem-like cells through expression of DNAJB8 by activation of heat shock factor 1.
Kusumoto H, Hirohashi Y, Nishizawa S, Yamashita M, Yasuda K, Murai A, Takaya A, Mori T, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Kondo T, Sato N, Hara I, Torigoe T. Kusumoto H, et al. Among authors: murai a. Cancer Sci. 2018 Mar;109(3):741-750. doi: 10.1111/cas.13501. Epub 2018 Feb 20. Cancer Sci. 2018. PMID: 29316077 Free PMC article.
Identification and functional analysis of variants of a cancer/testis antigen LEMD1 in colorectal cancer stem-like cells.
Takeda R, Hirohashi Y, Shen M, Wang L, Ogawa T, Murai A, Yamamoto E, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Nishidate T, Okita K, Kutomi G, Sato N, Takemasa I, Torigoe T. Takeda R, et al. Among authors: murai a. Biochem Biophys Res Commun. 2017 Apr 8;485(3):651-657. doi: 10.1016/j.bbrc.2017.02.081. Epub 2017 Feb 20. Biochem Biophys Res Commun. 2017. PMID: 28219643
LY6/PLAUR domain containing 3 has a role in the maintenance of colorectal cancer stem-like cells.
Wang L, Hirohashi Y, Ogawa T, Shen M, Takeda R, Murai A, Yamamoto E, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Nishidate T, Okita K, Kutomi G, Sato N, Takemasa I, Torigoe T. Wang L, et al. Among authors: murai a. Biochem Biophys Res Commun. 2017 Apr 29;486(2):232-238. doi: 10.1016/j.bbrc.2017.02.112. Epub 2017 Feb 24. Biochem Biophys Res Commun. 2017. PMID: 28238780
288 results