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Studying synapses in human brain with array tomography and electron microscopy.
Kay KR, Smith C, Wright AK, Serrano-Pozo A, Pooler AM, Koffie R, Bastin ME, Bak TH, Abrahams S, Kopeikina KJ, McGuone D, Frosch MP, Gillingwater TH, Hyman BT, Spires-Jones TL. Kay KR, et al. Nat Protoc. 2013;8(7):1366-80. doi: 10.1038/nprot.2013.078. Epub 2013 Jun 20. Nat Protoc. 2013. PMID: 23787894 Free PMC article.
Post-mortem brain analyses of the Lothian Birth Cohort 1936: extending lifetime cognitive and brain phenotyping to the level of the synapse.
Henstridge CM, Jackson RJ, Kim JM, Herrmann AG, Wright AK, Harris SE, Bastin ME, Starr JM, Wardlaw J, Gillingwater TH, Smith C, McKenzie CA, Cox SR, Deary IJ, Spires-Jones TL. Henstridge CM, et al. Acta Neuropathol Commun. 2015 Sep 4;3:53. doi: 10.1186/s40478-015-0232-0. Acta Neuropathol Commun. 2015. PMID: 26335101 Free PMC article.
Erratum to: Post-mortem brain analyses of the Lothian Birth Cohort 1936: extending lifetime cognitive and brain phenotyping to the level of the synapse.
Henstridge CM, Jackson RJ, Kim JM, Herrmann AG, Wright AK, Harris SE, Bastin ME, Starr JM, Wardlaw J, Gillingwater TH, Smith C, McKenzie CA, Cox SR, Deary IJ, Spires-Jones TL. Henstridge CM, et al. Acta Neuropathol Commun. 2015 Dec 9;3(1):83. doi: 10.1186/s40478-015-0244-9. Acta Neuropathol Commun. 2015. PMID: 26651483 Free PMC article.
Tau association with synaptic vesicles causes presynaptic dysfunction.
Zhou L, McInnes J, Wierda K, Holt M, Herrmann AG, Jackson RJ, Wang YC, Swerts J, Beyens J, Miskiewicz K, Vilain S, Dewachter I, Moechars D, De Strooper B, Spires-Jones TL, De Wit J, Verstreken P. Zhou L, et al. Nat Commun. 2017 May 11;8:15295. doi: 10.1038/ncomms15295. Nat Commun. 2017. PMID: 28492240 Free PMC article.
TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss.
Paolicelli RC, Jawaid A, Henstridge CM, Valeri A, Merlini M, Robinson JL, Lee EB, Rose J, Appel S, Lee VM, Trojanowski JQ, Spires-Jones T, Schulz PE, Rajendran L. Paolicelli RC, et al. Neuron. 2017 Jul 19;95(2):297-308.e6. doi: 10.1016/j.neuron.2017.05.037. Epub 2017 Jun 29. Neuron. 2017. PMID: 28669544 Free PMC article.
165 results