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Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8+ T cells.
Nguyen S, Deleage C, Darko S, Ransier A, Truong DP, Agarwal D, Japp AS, Wu VH, Kuri-Cervantes L, Abdel-Mohsen M, Del Rio Estrada PM, Ablanedo-Terrazas Y, Gostick E, Hoxie JA, Zhang NR, Naji A, Reyes-Terán G, Estes JD, Price DA, Douek DC, Deeks SG, Buggert M, Betts MR. Nguyen S, et al. Sci Transl Med. 2019 Dec 18;11(523):eaax4077. doi: 10.1126/scitranslmed.aax4077. Sci Transl Med. 2019. PMID: 31852798 Free PMC article.
CTLA-4+PD-1- Memory CD4+ T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques.
McGary CS, Deleage C, Harper J, Micci L, Ribeiro SP, Paganini S, Kuri-Cervantes L, Benne C, Ryan ES, Balderas R, Jean S, Easley K, Marconi V, Silvestri G, Estes JD, Sekaly RP, Paiardini M. McGary CS, et al. Immunity. 2017 Oct 17;47(4):776-788.e5. doi: 10.1016/j.immuni.2017.09.018. Immunity. 2017. PMID: 29045906 Free PMC article.
HIV-Specific CD8+ T Cells Exhibit Reduced and Differentially Regulated Cytolytic Activity in Lymphoid Tissue.
Reuter MA, Del Rio Estrada PM, Buggert M, Petrovas C, Ferrando-Martinez S, Nguyen S, Sada Japp A, Ablanedo-Terrazas Y, Rivero-Arrieta A, Kuri-Cervantes L, Gunzelman HM, Gostick E, Price DA, Koup RA, Naji A, Canaday DH, Reyes-Terán G, Betts MR. Reuter MA, et al. Cell Rep. 2017 Dec 19;21(12):3458-3470. doi: 10.1016/j.celrep.2017.11.075. Cell Rep. 2017. PMID: 29262326 Free PMC article.
CD32 is expressed on cells with transcriptionally active HIV but does not enrich for HIV DNA in resting T cells.
Abdel-Mohsen M, Kuri-Cervantes L, Grau-Exposito J, Spivak AM, Nell RA, Tomescu C, Vadrevu SK, Giron LB, Serra-Peinado C, Genescà M, Castellví J, Wu G, Del Rio Estrada PM, González-Navarro M, Lynn K, King CT, Vemula S, Cox K, Wan Y, Li Q, Mounzer K, Kostman J, Frank I, Paiardini M, Hazuda D, Reyes-Terán G, Richman D, Howell B, Tebas P, Martinez-Picado J, Planelles V, Buzon MJ, Betts MR, Montaner LJ. Abdel-Mohsen M, et al. Sci Transl Med. 2018 Apr 18;10(437):eaar6759. doi: 10.1126/scitranslmed.aar6759. Sci Transl Med. 2018. PMID: 29669853 Free PMC article.
Identification and characterization of HIV-specific resident memory CD8+ T cells in human lymphoid tissue.
Buggert M, Nguyen S, Salgado-Montes de Oca G, Bengsch B, Darko S, Ransier A, Roberts ER, Del Alcazar D, Brody IB, Vella LA, Beura L, Wijeyesinghe S, Herati RS, Del Rio Estrada PM, Ablanedo-Terrazas Y, Kuri-Cervantes L, Sada Japp A, Manne S, Vartanian S, Huffman A, Sandberg JK, Gostick E, Nadolski G, Silvestri G, Canaday DH, Price DA, Petrovas C, Su LF, Vahedi G, Dori Y, Frank I, Itkin MG, Wherry EJ, Deeks SG, Naji A, Reyes-Terán G, Masopust D, Douek DC, Betts MR. Buggert M, et al. Sci Immunol. 2018 Jun 1;3(24):eaar4526. doi: 10.1126/sciimmunol.aar4526. Sci Immunol. 2018. PMID: 29858286 Free PMC article.
T follicular helper cells in human efferent lymph retain lymphoid characteristics.
Vella LA, Buggert M, Manne S, Herati RS, Sayin I, Kuri-Cervantes L, Bukh Brody I, O'Boyle KC, Kaprielian H, Giles JR, Nguyen S, Muselman A, Antel JP, Bar-Or A, Johnson ME, Canaday DH, Naji A, Ganusov VV, Laufer TM, Wells AD, Dori Y, Itkin MG, Betts MR, Wherry EJ. Vella LA, et al. J Clin Invest. 2019 Jul 2;129(8):3185-3200. doi: 10.1172/JCI125628. eCollection 2019 Jul 2. J Clin Invest. 2019. PMID: 31264971 Free PMC article.
40 results