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A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination.
Klareskog L, Stolt P, Lundberg K, Källberg H, Bengtsson C, Grunewald J, Rönnelid J, Harris HE, Ulfgren AK, Rantapää-Dahlqvist S, Eklund A, Padyukov L, Alfredsson L. Klareskog L, et al. Arthritis Rheum. 2006 Jan;54(1):38-46. doi: 10.1002/art.21575. Arthritis Rheum. 2006. PMID: 16385494 Free article.
Up regulation of monocyte chemoattractant protein-1 expression in anti-citrulline antibody and immunoglobulin M rheumatoid factor positive subjects precedes onset of inflammatory response and development of overt rheumatoid arthritis.
Rantapää-Dahlqvist S, Boman K, Tarkowski A, Hallmans G. Rantapää-Dahlqvist S, et al. Ann Rheum Dis. 2007 Jan;66(1):121-3. doi: 10.1136/ard.2006.057331. Epub 2006 Jun 1. Ann Rheum Dis. 2007. PMID: 16740681 Free PMC article.
267 results