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Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance.
Downing T, Imamura H, Decuypere S, Clark TG, Coombs GH, Cotton JA, Hilley JD, de Doncker S, Maes I, Mottram JC, Quail MA, Rijal S, Sanders M, Schönian G, Stark O, Sundar S, Vanaerschot M, Hertz-Fowler C, Dujardin JC, Berriman M. Downing T, et al. Among authors: imamura h. Genome Res. 2011 Dec;21(12):2143-56. doi: 10.1101/gr.123430.111. Epub 2011 Oct 28. Genome Res. 2011. PMID: 22038251 Free PMC article.
Genome-wide SNP and microsatellite variation illuminate population-level epidemiology in the Leishmania donovani species complex.
Downing T, Stark O, Vanaerschot M, Imamura H, Sanders M, Decuypere S, de Doncker S, Maes I, Rijal S, Sundar S, Dujardin JC, Berriman M, Schönian G. Downing T, et al. Among authors: imamura h. Infect Genet Evol. 2012 Jan;12(1):149-59. doi: 10.1016/j.meegid.2011.11.005. Epub 2011 Nov 20. Infect Genet Evol. 2012. PMID: 22119748 Free PMC article.
In vitro selection of miltefosine resistance in promastigotes of Leishmania donovani from Nepal: genomic and metabolomic characterization.
Shaw CD, Lonchamp J, Downing T, Imamura H, Freeman TM, Cotton JA, Sanders M, Blackburn G, Dujardin JC, Rijal S, Khanal B, Illingworth CJ, Coombs GH, Carter KC. Shaw CD, et al. Among authors: imamura h. Mol Microbiol. 2016 Mar;99(6):1134-48. doi: 10.1111/mmi.13291. Epub 2016 Feb 9. Mol Microbiol. 2016. PMID: 26713880 Free PMC article.
Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent.
Imamura H, Downing T, Van den Broeck F, Sanders MJ, Rijal S, Sundar S, Mannaert A, Vanaerschot M, Berg M, De Muylder G, Dumetz F, Cuypers B, Maes I, Domagalska M, Decuypere S, Rai K, Uranw S, Bhattarai NR, Khanal B, Prajapati VK, Sharma S, Stark O, Schönian G, De Koning HP, Settimo L, Vanhollebeke B, Roy S, Ostyn B, Boelaert M, Maes L, Berriman M, Dujardin JC, Cotton JA. Imamura H, et al. Elife. 2016 Mar 22;5:e12613. doi: 10.7554/eLife.12613. Elife. 2016. PMID: 27003289 Free PMC article.
Modulation of Aneuploidy in Leishmania donovani during Adaptation to Different In Vitro and In Vivo Environments and Its Impact on Gene Expression.
Dumetz F, Imamura H, Sanders M, Seblova V, Myskova J, Pescher P, Vanaerschot M, Meehan CJ, Cuypers B, De Muylder G, Späth GF, Bussotti G, Vermeesch JR, Berriman M, Cotton JA, Volf P, Dujardin JC, Domagalska MA. Dumetz F, et al. Among authors: imamura h. mBio. 2017 May 23;8(3):e00599-17. doi: 10.1128/mBio.00599-17. mBio. 2017. PMID: 28536289 Free PMC article.
Haplotype selection as an adaptive mechanism in the protozoan pathogen Leishmania donovani.
Prieto Barja P, Pescher P, Bussotti G, Dumetz F, Imamura H, Kedra D, Domagalska M, Chaumeau V, Himmelbauer H, Pages M, Sterkers Y, Dujardin JC, Notredame C, Späth GF. Prieto Barja P, et al. Among authors: imamura h. Nat Ecol Evol. 2017 Dec;1(12):1961-1969. doi: 10.1038/s41559-017-0361-x. Epub 2017 Nov 6. Nat Ecol Evol. 2017. PMID: 29109466 Free article.
Integrated genomic and metabolomic profiling of ISC1, an emerging Leishmania donovani population in the Indian subcontinent.
Cuypers B, Berg M, Imamura H, Dumetz F, De Muylder G, Domagalska MA, Rijal S, Bhattarai NR, Maes I, Sanders M, Cotton JA, Meysman P, Laukens K, Dujardin JC. Cuypers B, et al. Among authors: imamura h. Infect Genet Evol. 2018 Aug;62:170-178. doi: 10.1016/j.meegid.2018.04.021. Epub 2018 Apr 19. Infect Genet Evol. 2018. PMID: 29679745 Free PMC article.
1,708 results