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A new tumor suppressor role for the Notch pathway in bladder cancer.
Rampias T, Vgenopoulou P, Avgeris M, Polyzos A, Stravodimos K, Valavanis C, Scorilas A, Klinakis A. Rampias T, et al. Among authors: klinakis a. Nat Med. 2014 Oct;20(10):1199-205. doi: 10.1038/nm.3678. Epub 2014 Sep 7. Nat Med. 2014. PMID: 25194568
Therapeutic effects of an anti-Myc drug on mouse pancreatic cancer.
Stellas D, Szabolcs M, Koul S, Li Z, Polyzos A, Anagnostopoulos C, Cournia Z, Tamvakopoulos C, Klinakis A, Efstratiadis A. Stellas D, et al. Among authors: klinakis a. J Natl Cancer Inst. 2014 Oct 11;106(12):dju320. doi: 10.1093/jnci/dju320. Print 2014 Dec. J Natl Cancer Inst. 2014. PMID: 25306215
The lysine-specific methyltransferase KMT2C/MLL3 regulates DNA repair components in cancer.
Rampias T, Karagiannis D, Avgeris M, Polyzos A, Kokkalis A, Kanaki Z, Kousidou E, Tzetis M, Kanavakis E, Stravodimos K, Manola KN, Pantelias GE, Scorilas A, Klinakis A. Rampias T, et al. Among authors: klinakis a. EMBO Rep. 2019 Mar;20(3):e46821. doi: 10.15252/embr.201846821. Epub 2019 Jan 21. EMBO Rep. 2019. PMID: 30665945 Free PMC article.
Notch controls urothelial integrity in the mouse bladder.
Paraskevopoulou V, Bonis V, Dionellis VS, Paschalidis N, Melissa P, Chavdoula E, Vasilaki E, Pateras IS, Klinakis A. Paraskevopoulou V, et al. Among authors: klinakis a. JCI Insight. 2020 Feb 13;5(3):e133232. doi: 10.1172/jci.insight.133232. JCI Insight. 2020. PMID: 32051338 Free PMC article.
Canonical NF-κB Promotes Lung Epithelial Cell Tumour Growth by Downregulating the Metastasis Suppressor CD82 and Enhancing Epithelial-to-Mesenchymal Cell Transition.
Roupakia E, Chavdoula E, Karpathiou G, Vatsellas G, Chatzopoulos D, Mela A, Gillette JM, Kriegsmann K, Kriegsmann M, Batistatou A, Goussia A, Marcu KB, Karteris E, Klinakis A, Kolettas E. Roupakia E, et al. Among authors: klinakis a. Cancers (Basel). 2021 Aug 26;13(17):4302. doi: 10.3390/cancers13174302. Cancers (Basel). 2021. PMID: 34503110 Free PMC article.
Loss of Kmt2c in vivo leads to EMT, mitochondrial dysfunction and improved response to lapatinib in breast cancer.
Simigdala N, Chalari A, Sklirou AD, Chavdoula E, Papafotiou G, Melissa P, Kafalidou A, Paschalidis N, Pateras IS, Athanasiadis E, Konstantopoulos D, Trougakos IP, Klinakis A. Simigdala N, et al. Among authors: klinakis a. Cell Mol Life Sci. 2023 Mar 18;80(4):100. doi: 10.1007/s00018-023-04734-7. Cell Mol Life Sci. 2023. PMID: 36933062 Free PMC article.
A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia.
Klinakis A, Lobry C, Abdel-Wahab O, Oh P, Haeno H, Buonamici S, van De Walle I, Cathelin S, Trimarchi T, Araldi E, Liu C, Ibrahim S, Beran M, Zavadil J, Efstratiadis A, Taghon T, Michor F, Levine RL, Aifantis I. Klinakis A, et al. Nature. 2011 May 12;473(7346):230-3. doi: 10.1038/nature09999. Nature. 2011. PMID: 21562564 Free PMC article.
61 results