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Preclinical profile of ITI-214, an inhibitor of phosphodiesterase 1, for enhancement of memory performance in rats.
Snyder GL, Prickaerts J, Wadenberg ML, Zhang L, Zheng H, Yao W, Akkerman S, Zhu H, Hendrick JP, Vanover KE, Davis R, Li P, Mates S, Wennogle LP. Snyder GL, et al. Among authors: wennogle lp. Psychopharmacology (Berl). 2016 Sep;233(17):3113-24. doi: 10.1007/s00213-016-4346-2. Epub 2016 Jun 24. Psychopharmacology (Berl). 2016. PMID: 27342643 Free PMC article.
Acute Enhancement of Cardiac Function by Phosphodiesterase Type 1 Inhibition.
Hashimoto T, Kim GE, Tunin RS, Adesiyun T, Hsu S, Nakagawa R, Zhu G, O'Brien JJ, Hendrick JP, Davis RE, Yao W, Beard D, Hoxie HR, Wennogle LP, Lee DI, Kass DA. Hashimoto T, et al. Among authors: wennogle lp. Circulation. 2018 Oct 30;138(18):1974-1987. doi: 10.1161/CIRCULATIONAHA.117.030490. Circulation. 2018. PMID: 30030415 Free PMC article.
Functional profile of a novel modulator of serotonin, dopamine, and glutamate neurotransmission.
Snyder GL, Vanover KE, Zhu H, Miller DB, O'Callaghan JP, Tomesch J, Li P, Zhang Q, Krishnan V, Hendrick JP, Nestler EJ, Davis RE, Wennogle LP, Mates S. Snyder GL, et al. Among authors: wennogle lp. Psychopharmacology (Berl). 2015 Feb;232(3):605-21. doi: 10.1007/s00213-014-3704-1. Epub 2014 Aug 15. Psychopharmacology (Berl). 2015. PMID: 25120104 Free PMC article.
Discovery of Potent and Selective Inhibitors of Phosphodiesterase 1 for the Treatment of Cognitive Impairment Associated with Neurodegenerative and Neuropsychiatric Diseases.
Li P, Zheng H, Zhao J, Zhang L, Yao W, Zhu H, Beard JD, Ida K, Lane W, Snell G, Sogabe S, Heyser CJ, Snyder GL, Hendrick JP, Vanover KE, Davis RE, Wennogle LP. Li P, et al. Among authors: wennogle lp. J Med Chem. 2016 Feb 11;59(3):1149-64. doi: 10.1021/acs.jmedchem.5b01751. Epub 2016 Feb 2. J Med Chem. 2016. PMID: 26789933
Discovery of a tetracyclic quinoxaline derivative as a potent and orally active multifunctional drug candidate for the treatment of neuropsychiatric and neurological disorders.
Li P, Zhang Q, Robichaud AJ, Lee T, Tomesch J, Yao W, Beard JD, Snyder GL, Zhu H, Peng Y, Hendrick JP, Vanover KE, Davis RE, Mates S, Wennogle LP. Li P, et al. Among authors: wennogle lp. J Med Chem. 2014 Mar 27;57(6):2670-82. doi: 10.1021/jm401958n. Epub 2014 Mar 5. J Med Chem. 2014. PMID: 24559051
Discovery of novel alpha7 nicotinic receptor antagonists.
Peng Y, Zhang Q, Snyder GL, Zhu H, Yao W, Tomesch J, Papke RL, O'Callaghan JP, Welsh WJ, Wennogle LP. Peng Y, et al. Among authors: wennogle lp. Bioorg Med Chem Lett. 2010 Aug 15;20(16):4825-30. doi: 10.1016/j.bmcl.2010.06.103. Epub 2010 Jun 25. Bioorg Med Chem Lett. 2010. PMID: 20638843 Free PMC article.
59 results