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Exploiting the passenger ACO1-deficiency arising from 9p21 deletions to kill T-cell lymphoblastic neoplasia cells.
Gonzalez-Sanchez L, Cobos-Fernandez MA, Lopez-Nieva P, Villa-Morales M, Stamatakis K, Cuezva JM, Marin-Rubio JL, Vazquez-Dominguez I, Gonzalez-Vasconcellos I, Salido E, Llamas P, Lopez-Lorenzo JL, Santos J, Fernandez-Piqueras J. Gonzalez-Sanchez L, et al. Carcinogenesis. 2020 Aug 12;41(8):1113-1122. doi: 10.1093/carcin/bgz185. Carcinogenesis. 2020. PMID: 31734690 Free article.
Contribution of JAK2 mutations to T-cell lymphoblastic lymphoma development.
Roncero AM, López-Nieva P, Cobos-Fernández MA, Villa-Morales M, González-Sánchez L, López-Lorenzo JL, Llamas P, Ayuso C, Rodríguez-Pinilla SM, Arriba MC, Piris MA, Fernández-Navarro P, Fernández AF, Fraga MF, Santos J, Fernández-Piqueras J. Roncero AM, et al. Leukemia. 2016 Jan;30(1):94-103. doi: 10.1038/leu.2015.202. Epub 2015 Jul 28. Leukemia. 2016. PMID: 26216197 Free PMC article.
Uveitis and Myositis as Immune Complications in Chemorefractory NK/T-Cell Nasal-Type Lymphoma Successfully Treated with Allogeneic Stem-Cell Transplant.
Gómez-Crespo MJ, García-Raso A, López-Lorenzo JL, Villaescusa T, Rodríguez-Pinilla M, Fortes J, Serrano C, Machan S, Llamas P, Córdoba R. Gómez-Crespo MJ, et al. Case Rep Hematol. 2016;2016:7297920. doi: 10.1155/2016/7297920. Epub 2016 Oct 11. Case Rep Hematol. 2016. PMID: 27807488 Free PMC article.
RNA-Seq reveals the existence of a CDKN1C-E2F1-TP53 axis that is altered in human T-cell lymphoblastic lymphomas.
López-Nieva P, Fernández-Navarro P, Vaquero-Lorenzo C, Villa-Morales M, Graña-Castro O, Cobos-Fernández MÁ, López-Lorenzo JL, Llamas P, González-Sanchez L, Sastre I, Pollan M, Malumbres M, Santos J, Fernández-Piqueras J. López-Nieva P, et al. BMC Cancer. 2018 Apr 16;18(1):430. doi: 10.1186/s12885-018-4304-y. BMC Cancer. 2018. PMID: 29661169 Free PMC article.
Downregulation of specific FBXW7 isoforms with differential effects in T-cell lymphoblastic lymphoma.
Vázquez-Domínguez I, González-Sánchez L, López-Nieva P, Fernández-Navarro P, Villa-Morales M, Cobos-Fernández MÁ, Sastre I, F Fraga M, F Fernández A, Malumbres M, Salazar-Roa M, Graña-Castro O, Santos J, Llamas P, López-Lorenzo JL, Fernández-Piqueras J. Vázquez-Domínguez I, et al. Oncogene. 2019 Jun;38(23):4620-4636. doi: 10.1038/s41388-019-0746-1. Epub 2019 Feb 11. Oncogene. 2019. PMID: 30742097
Three monocytic neoplasms in a single patient.
Pérez-Sáenz MA, Rodriguez-Pinilla SM, Salgado RN, Carvajal N, Serrano C, Soto C, Serrano J, Atance M, López-Lorenzo JL, Requena L, Rojo F, Piris MA, Llamas P, Alonso-Dominguez JM. Pérez-Sáenz MA, et al. Leuk Lymphoma. 2020 Oct;61(10):2523-2526. doi: 10.1080/10428194.2020.1761966. Epub 2020 May 25. Leuk Lymphoma. 2020. PMID: 32449424 No abstract available.
Progression of myeloproliferative neoplasm with BCR::JAK2 fusion to acute leukemia of ambiguous lineage.
Suárez EU, Piris MÁ, Rodríguez-Pinilla SM, García JF, López-Lorenzo JL, Cornago-Navascués J, Salgado-Sánchez R, Castaño-Bonilla T, Mata-Serna R, Alonso-Domínguez JM, Llamas P. Suárez EU, et al. Among authors: lopez lorenzo jl. Ann Hematol. 2024 May;103(5):1797-1799. doi: 10.1007/s00277-024-05647-6. Epub 2024 Feb 3. Ann Hematol. 2024. PMID: 38308706 No abstract available.
Feasibility of treatment discontinuation in chronic myeloid leukemia in clinical practice: results from a nationwide series of 236 patients.
Hernández-Boluda JC, Pereira A, Pastor-Galán I, Alvarez-Larrán A, Savchuk A, Puerta JM, Sánchez-Pina JM, Collado R, Díaz-González A, Angona A, Sagüés M, García-Gutiérrez V, Boqué C, Osorio S, Vallansot R, Palomera L, Mendizábal A, Casado LF, Pérez-Encinas M, Pérez-López R, Ferrer-Marín F, Sánchez-Guijo F, García C, Heras NL, López-Lorenzo JL, Cervantes F, Steegmann JL; Grupo Español de Leucemia Mieloide Crónica (GELMC). Hernández-Boluda JC, et al. Blood Cancer J. 2018 Dec 2;8(10):91. doi: 10.1038/s41408-018-0125-0. Blood Cancer J. 2018. PMID: 30504932 Free PMC article.
Clinically relevant gene editing in hematopoietic stem cells for the treatment of pyruvate kinase deficiency.
Fañanas-Baquero S, Quintana-Bustamante O, Dever DP, Alberquilla O, Sanchez-Dominguez R, Camarena J, Ojeda-Perez I, Dessy-Rodriguez M, Turk R, Schubert MS, Lattanzi A, Xu L, Lopez-Lorenzo JL, Bianchi P, Bueren JA, Behlke MA, Porteus M, Segovia JC. Fañanas-Baquero S, et al. Mol Ther Methods Clin Dev. 2021 May 14;22:237-248. doi: 10.1016/j.omtm.2021.05.001. eCollection 2021 Sep 10. Mol Ther Methods Clin Dev. 2021. PMID: 34485608 Free PMC article.
Who should be eligible for gene therapy clinical trials in red blood cell pyruvate kinase deficiency (PKD)?: Toward an expanded definition of severe PKD.
Schwartz JD, Barcellini W, Grace RF, Bianchi P, Zanella A, López Lorenzo JL, Sevilla J, Shah AJ, Glader B, Nicoletti E, Navarro Ordoñez S, Segovia JC. Schwartz JD, et al. Am J Hematol. 2022 Mar 1;97(3):E120-E125. doi: 10.1002/ajh.26458. Epub 2022 Jan 24. Am J Hematol. 2022. PMID: 34989415 Free PMC article. Review. No abstract available.
49 results