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Synthesis of Novel Nicotinic Ligands with Multimodal Action: Targeting Acetylcholine α4β2, Dopamine and Serotonin Transporters.
González-Gutiérrez JP, Pessoa-Mahana HA, Iturriaga-Vásquez PE, Reyes-Parada MI, Guerra-Díaz NE, Hodar-Salazar M, Viscarra F, Paillali P, Núñez-Vivanco G, Lorca-Carvajal MA, Mella-Raipán J, Zúñiga MC. González-Gutiérrez JP, et al. Among authors: reyes parada mi. Molecules. 2019 Oct 22;24(20):3808. doi: 10.3390/molecules24203808. Molecules. 2019. PMID: 31652614 Free PMC article.
Synthesis, Docking, 3-D-Qsar, and Biological Assays of Novel Indole Derivatives Targeting Serotonin Transporter, Dopamine D2 Receptor, and Mao-A Enzyme: In the Pursuit for Potential Multitarget Directed Ligands.
Cerda-Cavieres C, Quiroz G, Iturriaga-Vásquez P, Rodríguez-Lavado J, Alarcón-Espósito J, Saitz C, Pessoa-Mahana CD, Chung H, Araya-Maturana R, Mella-Raipán J, Cabezas D, Ojeda-Gómez C, Reyes-Parada M, Pessoa-Mahana H. Cerda-Cavieres C, et al. Molecules. 2020 Oct 10;25(20):4614. doi: 10.3390/molecules25204614. Molecules. 2020. PMID: 33050524 Free PMC article.
Pharmacological Characterization of 4-Methylthioamphetamine Derivatives.
Guajardo FG, Velásquez VB, Raby D, Núñez-Vivanco G, Iturriaga-Vásquez P, España RA, Reyes-Parada M, Sotomayor-Zárate R. Guajardo FG, et al. Molecules. 2020 Nov 13;25(22):5310. doi: 10.3390/molecules25225310. Molecules. 2020. PMID: 33203055 Free PMC article.
Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer's disease.
Rodríguez-Lavado J, Gallardo-Garrido C, Mallea M, Bustos V, Osorio R, Hödar-Salazar M, Chung H, Araya-Maturana R, Lorca M, Pessoa-Mahana CD, Mella-Raipán J, Saitz C, Jaque P, Reyes-Parada M, Iturriaga-Vásquez P, Pessoa-Mahana H. Rodríguez-Lavado J, et al. Eur J Med Chem. 2020 Jul 15;198:112368. doi: 10.1016/j.ejmech.2020.112368. Epub 2020 Apr 29. Eur J Med Chem. 2020. PMID: 32388114
Synthesis, docking and pharmacological evaluation of novel homo- and hetero-bis 3-piperazinylpropylindole derivatives at SERT and 5-HT1A receptor.
Pessoa-Mahana H, González-Lira C, Fierro A, Zapata-Torres G, Pessoa-Mahana CD, Ortiz-Severin J, Iturriaga-Vásquez P, Reyes-Parada M, Silva-Matus P, Saitz-Barría C, Araya-Maturana R. Pessoa-Mahana H, et al. Bioorg Med Chem. 2013 Dec 15;21(24):7604-11. doi: 10.1016/j.bmc.2013.10.036. Epub 2013 Nov 6. Bioorg Med Chem. 2013. PMID: 24262884
Similarities between the Binding Sites of SB-206553 at Serotonin Type 2 and Alpha7 Acetylcholine Nicotinic Receptors: Rationale for Its Polypharmacological Profile.
Möller-Acuña P, Contreras-Riquelme JS, Rojas-Fuentes C, Nuñez-Vivanco G, Alzate-Morales J, Iturriaga-Vásquez P, Arias HR, Reyes-Parada M. Möller-Acuña P, et al. PLoS One. 2015 Aug 5;10(8):e0134444. doi: 10.1371/journal.pone.0134444. eCollection 2015. PLoS One. 2015. PMID: 26244344 Free PMC article.
56 results