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Structural analysis of pathogenic mutations targeting Glu427 of ALDH7A1, the hot spot residue of pyridoxine-dependent epilepsy.
J Inherit Metab Dis. 2020 May;43(3):635-644. doi: 10.1002/jimd.12184. Epub 2019 Dec 1.
J Inherit Metab Dis. 2020.
PMID: 31652343
Free PMC article.
Importance of the C-Terminus of Aldehyde Dehydrogenase 7A1 for Oligomerization and Catalytic Activity.
Korasick DA, Wyatt JW, Luo M, Laciak AR, Ruddraraju K, Gates KS, Henzl MT, Tanner JJ.
Korasick DA, et al. Among authors: laciak ar.
Biochemistry. 2017 Nov 7;56(44):5910-5919. doi: 10.1021/acs.biochem.7b00803.
Biochemistry. 2017.
PMID: 29045138
Free PMC article.
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Structural and biochemical consequences of pyridoxine-dependent epilepsy mutations that target the aldehyde binding site of aldehyde dehydrogenase ALDH7A1.
Laciak AR, Korasick DA, Wyatt JW, Gates KS, Tanner JJ.
Laciak AR, et al.
FEBS J. 2020 Jan;287(1):173-189. doi: 10.1111/febs.14997. Epub 2019 Jul 25.
FEBS J. 2020.
PMID: 31302938
Free PMC article.
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Covalent Allosteric Inactivation of Protein Tyrosine Phosphatase 1B (PTP1B) by an Inhibitor-Electrophile Conjugate.
Punthasee P, Laciak AR, Cummings AH, Ruddraraju KV, Lewis SM, Hillebrand R, Singh H, Tanner JJ, Gates KS.
Punthasee P, et al. Among authors: laciak ar.
Biochemistry. 2017 Apr 11;56(14):2051-2060. doi: 10.1021/acs.biochem.7b00151. Epub 2017 Apr 3.
Biochemistry. 2017.
PMID: 28345882
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Inactivation of protein tyrosine phosphatases by dietary isothiocyanates.
Lewis SM, Li Y, Catalano MJ, Laciak AR, Singh H, Seiner DR, Reilly TJ, Tanner JJ, Gates KS.
Lewis SM, et al. Among authors: laciak ar.
Bioorg Med Chem Lett. 2015 Oct 15;25(20):4549-52. doi: 10.1016/j.bmcl.2015.08.065. Epub 2015 Aug 24.
Bioorg Med Chem Lett. 2015.
PMID: 26338358
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Structural analysis of the catalytic domain of Artemis endonuclease/SNM1C reveals distinct structural features.
Karim MF, Liu S, Laciak AR, Volk L, Koszelak-Rosenblum M, Lieber MR, Wu M, Curtis R, Huang NN, Carr G, Zhu G.
Karim MF, et al. Among authors: laciak ar.
J Biol Chem. 2020 Aug 28;295(35):12368-12377. doi: 10.1074/jbc.RA120.014136. Epub 2020 Jun 23.
J Biol Chem. 2020.
PMID: 32576658
Free PMC article.
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Structure and Function of SNM1 Family Nucleases.
Wu HY, Zheng Y, Laciak AR, Huang NN, Koszelak-Rosenblum M, Flint AJ, Carr G, Zhu G.
Wu HY, et al. Among authors: laciak ar.
Adv Exp Med Biol. 2023;1414:1-26. doi: 10.1007/5584_2022_724.
Adv Exp Med Biol. 2023.
PMID: 35708844
Review.
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