Harris G - Search Results

1

Structure-Guided Enhancement of Selectivity of Chemical Probe Inhibitors Targeting Bacterial Seryl-tRNA Synthetase.

Cain R, Salimraj R, Punekar AS, Bellini D, Fishwick CWG, Czaplewski L, Scott DJ, Harris G, Dowson CG, Lloyd AJ, Roper DI. Cain R, et al. Among authors: harris g. J Med Chem. 2019 Nov 14;62(21):9703-9717. doi: 10.1021/acs.jmedchem.9b01131. Epub 2019 Nov 5. J Med Chem. 2019. PMID: 31626547 Free article.

2

Structural modeling of an outer membrane electron conduit from a metal-reducing bacterium suggests electron transfer via periplasmic redox partners.

Edwards MJ, White GF, Lockwood CW, Lawes MC, Martel A, Harris G, Scott DJ, Richardson DJ, Butt JN, Clarke TA. Edwards MJ, et al. Among authors: harris g. J Biol Chem. 2018 May 25;293(21):8103-8112. doi: 10.1074/jbc.RA118.001850. Epub 2018 Apr 10. J Biol Chem. 2018. PMID: 29636412 Free PMC article.

3

The carbonic anhydrase of Clostridium autoethanogenum represents a new subclass of β-carbonic anhydrases.

Pander B, Harris G, Scott DJ, Winzer K, Köpke M, Simpson SD, Minton NP, Henstra AM. Pander B, et al. Among authors: harris g. Appl Microbiol Biotechnol. 2019 Sep;103(17):7275-7286. doi: 10.1007/s00253-019-10015-w. Epub 2019 Jul 25. Appl Microbiol Biotechnol. 2019. PMID: 31346685 Free PMC article.

4

The Vip3Ag4 Insecticidal Protoxin from Bacillus thuringiensis Adopts A Tetrameric Configuration That Is Maintained on Proteolysis.

Palma L, Scott DJ, Harris G, Din SU, Williams TL, Roberts OJ, Young MT, Caballero P, Berry C. Palma L, et al. Among authors: harris g. Toxins (Basel). 2017 May 14;9(5):165. doi: 10.3390/toxins9050165. Toxins (Basel). 2017. PMID: 28505109 Free PMC article.

5

Allosteric inhibition of human exonuclease1 (hExo1) through a novel extended β-sheet conformation.

Umar AA, Liddell S, Hussain R, Siligardi G, Harris G, Carr S, Asiani K, Gowers DM, Odell M, Scott DJ. Umar AA, et al. Among authors: harris g. Biochim Biophys Acta Gen Subj. 2020 Dec;1864(12):129730. doi: 10.1016/j.bbagen.2020.129730. Epub 2020 Sep 12. Biochim Biophys Acta Gen Subj. 2020. PMID: 32926959

6

Antiproliferative and Antimigratory Effects of a Novel YAP-TEAD Interaction Inhibitor Identified Using in Silico Molecular Docking.

Smith SA, Sessions RB, Shoemark DK, Williams C, Ebrahimighaei R, McNeill MC, Crump MP, McKay TR, Harris G, Newby AC, Bond M. Smith SA, et al. Among authors: harris g. J Med Chem. 2019 Feb 14;62(3):1291-1305. doi: 10.1021/acs.jmedchem.8b01402. Epub 2019 Jan 31. J Med Chem. 2019. PMID: 30640473 Free PMC article.

7

Engineering the Human Fc Region Enables Direct Cell Killing by Cancer Glycan-Targeting Antibodies without the Need for Immune Effector Cells or Complement.

Vankemmelbeke M, McIntosh RS, Chua JX, Kirk T, Daniels I, Patsalidou M, Moss R, Parsons T, Scott D, Harris G, Ramage JM, Spendlove I, Durrant LG. Vankemmelbeke M, et al. Among authors: harris g. Cancer Res. 2020 Aug 15;80(16):3399-3412. doi: 10.1158/0008-5472.CAN-19-3599. Epub 2020 Jun 12. Cancer Res. 2020. PMID: 32532823 Free PMC article.

8

Distinctive phosphoinositide- and Ca²⁺-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain.

Posner MG, Upadhyay A, Ishima R, Kalli AC, Harris G, Kremerskothen J, Sansom MSP, Crennell SJ, Bagby S. Posner MG, et al. Among authors: harris g. J Biol Chem. 2018 Jun 15;293(24):9335-9344. doi: 10.1074/jbc.RA118.002279. Epub 2018 May 3. J Biol Chem. 2018. PMID: 29724824 Free PMC article.

9

The streptococcal binding site in the gelatin-binding domain of fibronectin is consistent with a non-linear arrangement of modules.

Atkin KE, Brentnall AS, Harris G, Bingham RJ, Erat MC, Millard CJ, Schwarz-Linek U, Staunton D, Vakonakis I, Campbell ID, Potts JR. Atkin KE, et al. Among authors: harris g. J Biol Chem. 2010 Nov 19;285(47):36977-83. doi: 10.1074/jbc.M110.156935. Epub 2010 Sep 15. J Biol Chem. 2010. PMID: 20843804 Free PMC article.

10

Cloning, purification and structure determination of the HIV integrase-binding domain of lens epithelium-derived growth factor.

Hannon C, Cruz-Migoni A, Platonova O, Owen RL, Nettleship JE, Miller A, Carr SB, Harris G, Rabbitts TH, Phillips SEV. Hannon C, et al. Among authors: harris g. Acta Crystallogr F Struct Biol Commun. 2018 Mar 1;74(Pt 3):143-149. doi: 10.1107/S2053230X18001553. Epub 2018 Feb 26. Acta Crystallogr F Struct Biol Commun. 2018. PMID: 29497017 Free PMC article.

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