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A nonallergenic birch pollen allergy vaccine consisting of hepatitis PreS-fused Bet v 1 peptides focuses blocking IgG toward IgE epitopes and shifts immune responses to a tolerogenic and Th1 phenotype.
Marth K, Breyer I, Focke-Tejkl M, Blatt K, Shamji MH, Layhadi J, Gieras A, Swoboda I, Zafred D, Keller W, Valent P, Durham SR, Valenta R. Marth K, et al. J Immunol. 2013 Apr 1;190(7):3068-78. doi: 10.4049/jimmunol.1202441. Epub 2013 Feb 25. J Immunol. 2013. PMID: 23440415 Free PMC article.
Mucosal IgE immune responses in respiratory diseases.
Eguiluz-Gracia I, Layhadi JA, Rondon C, Shamji MH. Eguiluz-Gracia I, et al. Among authors: layhadi ja. Curr Opin Pharmacol. 2019 Jun;46:100-107. doi: 10.1016/j.coph.2019.05.009. Epub 2019 Jun 17. Curr Opin Pharmacol. 2019. PMID: 31220711 Review.
Allergen-specific IgG+ memory B cells are temporally linked to IgE memory responses.
Hoof I, Schulten V, Layhadi JA, Stranzl T, Christensen LH, Herrera de la Mata S, Seumois G, Vijayanand P, Lundegaard C, Niss K, Lund A, Ahrenfeldt J, Holm J, Steveling E, Sharif H, Durham SR, Peters B, Shamji MH, Andersen PS. Hoof I, et al. Among authors: layhadi ja. J Allergy Clin Immunol. 2020 Jul;146(1):180-191. doi: 10.1016/j.jaci.2019.11.046. Epub 2019 Dec 27. J Allergy Clin Immunol. 2020. PMID: 31883847 Free PMC article. Clinical Trial.
38 results