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Lack of Impact by SCY-078, a First-in-Class Oral Fungicidal Glucan Synthase Inhibitor, on the Pharmacokinetics of Rosiglitazone, a Substrate for CYP450 2C8, Supports the Low Risk for Clinically Relevant Metabolic Drug-Drug Interactions.
Wring S, Murphy G, Atiee G, Corr C, Hyman M, Willett M, Angulo D. Wring S, et al. J Clin Pharmacol. 2018 Oct;58(10):1305-1313. doi: 10.1002/jcph.1146. Epub 2018 May 10. J Clin Pharmacol. 2018. PMID: 29746713 Free PMC article. Clinical Trial.
Pharmacokinetics, Safety, and Tolerability of Single Oral Doses of a Novel Oxytocin Receptor Antagonist-Cligosiban-in Development for Premature Ejaculation: Three Randomized Clinical Trials in Healthy Subjects.
Osterloh IH, Muirhead GJ, Sultana S, Whaley S, van den Berg F, Atiee G. Osterloh IH, et al. Among authors: atiee g. J Sex Med. 2018 Nov;15(11):1547-1557. doi: 10.1016/j.jsxm.2018.09.006. Epub 2018 Oct 16. J Sex Med. 2018. PMID: 30341006 Clinical Trial.
First-in-Human Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of an Oral Formulation of DS-1040, an Inhibitor of the Activated Form of Thrombin-Activatable Fibrinolysis Inhibitor, in Healthy Subjects.
Zhou J, Limsakun T, Yin O, Warren V, Zamora C, Atiee G, Kochan J, Pav J, Kobayashi F, Vashi V, Dishy V. Zhou J, et al. J Clin Pharmacol. 2019 Dec;59(12):1669-1677. doi: 10.1002/jcph.1474. Epub 2019 Jun 27. J Clin Pharmacol. 2019. PMID: 31243790 Clinical Trial.
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