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Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.
Joshi K, de Massy MR, Ismail M, Reading JL, Uddin I, Woolston A, Hatipoglu E, Oakes T, Rosenthal R, Peacock T, Ronel T, Noursadeghi M, Turati V, Furness AJS, Georgiou A, Wong YNS, Ben Aissa A, Sunderland MW, Jamal-Hanjani M, Veeriah S, Birkbak NJ, Wilson GA, Hiley CT, Ghorani E, Guerra-Assunção JA, Herrero J, Enver T, Hadrup SR, Hackshaw A, Peggs KS, McGranahan N, Swanton C; TRACERx consortium; Quezada SA, Chain B. Joshi K, et al. Among authors: ghorani e. Nat Med. 2019 Oct;25(10):1549-1559. doi: 10.1038/s41591-019-0592-2. Epub 2019 Oct 7. Nat Med. 2019. PMID: 31591606 Free PMC article.
Immunotherapy for GTN: a new paradigm.
Baas IO, Westermann AM, You B, Bolze PA, Seckl M, Ghorani E. Baas IO, et al. Among authors: ghorani e. Gynecol Obstet Invest. 2023 Sep 13. doi: 10.1159/000533972. Online ahead of print. Gynecol Obstet Invest. 2023. PMID: 37703867 Free article. Review.
REFINE (REduced Frequency ImmuNE checkpoint inhibition in cancers): A multi-arm phase II basket trial testing reduced intensity immunotherapy across different cancers.
Merrick S, Nankivell M, Quartagno M, Clarke CS, Joharatnam-Hogan N, Waddell T, O'Carrigan B, Seckl M, Ghorani E, Banks E, Edmonds K, Bray G, Woodward R, Bennett R, Badrock J, Hudson W, Langley RE, Vasudev N, Pickering L, Gilbert DC. Merrick S, et al. Among authors: ghorani e. Contemp Clin Trials. 2023 Jan;124:107030. doi: 10.1016/j.cct.2022.107030. Epub 2022 Nov 26. Contemp Clin Trials. 2023. PMID: 36519749 Free PMC article. Clinical Trial.
Platinum-Based Chemotherapy Attenuates the Effector Response of CD8 T Cells to Concomitant PD-1 Blockade.
Mariniello A, Nasti TH, Chang DY, Hashimoto M, Malik S, McManus DT, Lee J, McGuire DJ, Cardenas MA, Umana P, Nicolini V, Antia R, Saha A, Buchwald Z, Kissick H, Ghorani E, Novello S, Sangiolo D, Scagliotti GV, Ramalingam SS, Ahmed R. Mariniello A, et al. Among authors: ghorani e. Clin Cancer Res. 2024 May 1;30(9):1833-1845. doi: 10.1158/1078-0432.CCR-23-1316. Clin Cancer Res. 2024. PMID: 37992307 Free PMC article.
47 results