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4th ESPT Conference: pharmacogenomics and personalized medicine - research progress and clinical implementation.
Sipeky C, Llerena A, Manolopoulos VG, Pearson E, Mlakar V, Gozzo L, Simmaco M, Marchetti P, Re MD, Stankovic S, Meyer U, Cascorbi I, Ingelman-Sundberg M, Suarez-Kurtz G, Marc J, Katsila T, Paulmichl M, Nofziger C, Ansari M, Drago F, van Schaik RH. Sipeky C, et al. Among authors: pearson e. Pharmacogenomics. 2019 Oct;20(15):1063-1069. doi: 10.2217/pgs-2019-0095. Pharmacogenomics. 2019. PMID: 31588876
Drug-drug-gene interactions and adverse drug reactions.
Malki MA, Pearson ER. Malki MA, et al. Pharmacogenomics J. 2020 Jun;20(3):355-366. doi: 10.1038/s41397-019-0122-0. Epub 2019 Dec 3. Pharmacogenomics J. 2020. PMID: 31792369 Free PMC article. Review.
Precision Medicine in Type 2 Diabetes: Clinical Markers of Insulin Resistance Are Associated With Altered Short- and Long-term Glycemic Response to DPP-4 Inhibitor Therapy.
Dennis JM, Shields BM, Hill AV, Knight BA, McDonald TJ, Rodgers LR, Weedon MN, Henley WE, Sattar N, Holman RR, Pearson ER, Hattersley AT, Jones AG; MASTERMIND Consortium. Dennis JM, et al. Among authors: pearson er. Diabetes Care. 2018 Apr;41(4):705-712. doi: 10.2337/dc17-1827. Epub 2018 Jan 31. Diabetes Care. 2018. PMID: 29386249 Free PMC article.
Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin.
Zhou K, Yee SW, Seiser EL, van Leeuwen N, Tavendale R, Bennett AJ, Groves CJ, Coleman RL, van der Heijden AA, Beulens JW, de Keyser CE, Zaharenko L, Rotroff DM, Out M, Jablonski KA, Chen L, Javorský M, Židzik J, Levin AM, Williams LK, Dujic T, Semiz S, Kubo M, Chien HC, Maeda S, Witte JS, Wu L, Tkáč I, Kooy A, van Schaik RHN, Stehouwer CDA, Logie L; MetGen Investigators; DPP Investigators; ACCORD Investigators; Sutherland C, Klovins J, Pirags V, Hofman A, Stricker BH, Motsinger-Reif AA, Wagner MJ, Innocenti F, 't Hart LM, Holman RR, McCarthy MI, Hedderson MM, Palmer CNA, Florez JC, Giacomini KM, Pearson ER. Zhou K, et al. Among authors: pearson er. Nat Genet. 2016 Sep;48(9):1055-1059. doi: 10.1038/ng.3632. Epub 2016 Aug 8. Nat Genet. 2016. PMID: 27500523 Free PMC article.
Predicting post one-year durability of glucose-lowering monotherapies in patients with newly-diagnosed type 2 diabetes mellitus - A MASTERMIND precision medicine approach (UKPDS 87).
Agbaje OF, Coleman RL, Hattersley AT, Jones AG, Pearson ER, Shields BM, Holman RR; MASTERMIND consortium. Agbaje OF, et al. Diabetes Res Clin Pract. 2020 Aug;166:108333. doi: 10.1016/j.diabres.2020.108333. Epub 2020 Jul 21. Diabetes Res Clin Pract. 2020. PMID: 32702468 Clinical Trial.
817 results