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Phosphatidylinositol 3-kinase inhibition potentiates glucocorticoid response in B-cell acute lymphoblastic leukemia.
Evangelisti C, Cappellini A, Oliveira M, Fragoso R, Barata JT, Bertaina A, Locatelli F, Simioni C, Neri LM, Chiarini F, Lonetti A, Buontempo F, Orsini E, Pession A, Manzoli L, Martelli AM, Evangelisti C. Evangelisti C, et al. J Cell Physiol. 2018 Mar;233(3):1796-1811. doi: 10.1002/jcp.26135. Epub 2017 Sep 7. J Cell Physiol. 2018. PMID: 28777460
PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis.
Garcia EG, Veloso A, Oliveira ML, Allen JR, Loontiens S, Brunson D, Do D, Yan C, Morris R, Iyer S, Garcia SP, Iftimia N, Van Loocke W, Matthijssens F, McCarthy K, Barata JT, Speleman F, Taghon T, Gutierrez A, Van Vlierberghe P, Haas W, Blackburn JS, Langenau DM. Garcia EG, et al. Among authors: oliveira ml. Leukemia. 2021 Mar;35(3):679-690. doi: 10.1038/s41375-020-0937-3. Epub 2020 Jun 30. Leukemia. 2021. PMID: 32606318 Free PMC article.
Interleukin-7 receptor α mutational activation can initiate precursor B-cell acute lymphoblastic leukemia.
Almeida ARM, Neto JL, Cachucho A, Euzébio M, Meng X, Kim R, Fernandes MB, Raposo B, Oliveira ML, Ribeiro D, Fragoso R, Zenatti PP, Soares T, de Matos MR, Corrêa JR, Duque M, Roberts KG, Gu Z, Qu C, Pereira C, Pyne S, Pyne NJ, Barreto VM, Bernard-Pierrot I, Clappier E, Mullighan CG, Grosso AR, Yunes JA, Barata JT. Almeida ARM, et al. Among authors: oliveira ml. Nat Commun. 2021 Dec 14;12(1):7268. doi: 10.1038/s41467-021-27197-5. Nat Commun. 2021. PMID: 34907175 Free PMC article.
CASZ1 upregulates PI3K-AKT-mTOR signaling and promotes T-cell acute lymphoblastic leukemia.
Cardoso BA, Duque M, Gírio A, Fragoso R, Oliveira ML, Allen JR, Martins LR, Correia NC, Silveira AB, Veloso A, Kimura S, Demoen L, Matthijssens F, Jeha S, Cheng C, Pui CH, Grosso AR, Neto JL, De Almeida SF, Van Vlieberghe P, Mullighan CG, Yunes JA, Langenau DM, Pflumio F, Barata JT. Cardoso BA, et al. Among authors: oliveira ml. Haematologica. 2023 Dec 7. doi: 10.3324/haematol.2023.282854. Online ahead of print. Haematologica. 2023. PMID: 38058200 Free article.
Differential activation of basal and IL-7-induced PI3K/Akt/mTOR and JAK/STAT5 signaling distinguishes pediatric from adult acute lymphoblastic leukemia.
Fernandes MB, Gomes AM, Oliveira ML, Caldas J, Lúcio P, Kim R, Caye-Eude A, Pereira F, De Sousa AB, De Stefano A, Follo MY, Soares MV, Lacerda JF, Desterro J, Cavé H, Clappier E, Duarte X, Ribeiro P, Barata JT. Fernandes MB, et al. Among authors: oliveira ml. Haematologica. 2024 Apr 24. doi: 10.3324/haematol.2023.284102. Online ahead of print. Haematologica. 2024. PMID: 38654666 Free article.
620 results