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Humanization by variable domain resurfacing and grafting on a human IgG4, using a new approach for determination of non-human like surface accessible framework residues based on homology modelling of variable domains.
Staelens S, Desmet J, Ngo TH, Vauterin S, Pareyn I, Barbeaux P, Van Rompaey I, Stassen JM, Deckmyn H, Vanhoorelbeke K. Staelens S, et al. Mol Immunol. 2006 Mar;43(8):1243-57. doi: 10.1016/j.molimm.2005.07.018. Epub 2005 Aug 22. Mol Immunol. 2006. PMID: 16118019
New approaches for antithrombotic antiplatelet therapies.
Ulrichts H, Vanhoorelbeke K, Van De Walle G, Katsutani S, De Meyer S, Staelens S, Deckmyn H. Ulrichts H, et al. Among authors: staelens s. Curr Med Chem. 2004 Sep;11(17):2261-3. doi: 10.2174/0929867043364630. Curr Med Chem. 2004. PMID: 15379711 Review.
In Vivo Cerebral Imaging of Mutant Huntingtin Aggregates Using 11C-CHDI-180R PET in a Nonhuman Primate Model of Huntington Disease.
Bertoglio D, Weiss AR, Liguore W, Martin LD, Hobbs T, Templon J, Srinivasan S, Dominguez C, Munoz-Sanjuan I, Khetarpal V, Verhaeghe J, Staelens S, Link J, Liu L, Bard JA, McBride JL. Bertoglio D, et al. Among authors: staelens s. J Nucl Med. 2023 Oct;64(10):1581-1587. doi: 10.2967/jnumed.123.265569. Epub 2023 Aug 17. J Nucl Med. 2023. PMID: 37591545 Free PMC article.
176 results