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The Drug Rediscovery protocol facilitates the expanded use of existing anticancer drugs.
van der Velden DL, Hoes LR, van der Wijngaart H, van Berge Henegouwen JM, van Werkhoven E, Roepman P, Schilsky RL, de Leng WWJ, Huitema ADR, Nuijen B, Nederlof PM, van Herpen CML, de Groot DJA, Devriese LA, Hoeben A, de Jonge MJA, Chalabi M, Smit EF, de Langen AJ, Mehra N, Labots M, Kapiteijn E, Sleijfer S, Cuppen E, Verheul HMW, Gelderblom H, Voest EE. van der Velden DL, et al. Among authors: schilsky rl. Nature. 2019 Oct;574(7776):127-131. doi: 10.1038/s41586-019-1600-x. Epub 2019 Sep 30. Nature. 2019. PMID: 31570881 Clinical Trial.
Implementing personalized cancer care.
Schilsky RL. Schilsky RL. Nat Rev Clin Oncol. 2014 Jul;11(7):432-8. doi: 10.1038/nrclinonc.2014.54. Epub 2014 Apr 1. Nat Rev Clin Oncol. 2014. PMID: 24687035 Review.
The evidence framework for precision cancer medicine.
Moscow JA, Fojo T, Schilsky RL. Moscow JA, et al. Among authors: schilsky rl. Nat Rev Clin Oncol. 2018 Mar;15(3):183-192. doi: 10.1038/nrclinonc.2017.186. Epub 2017 Dec 19. Nat Rev Clin Oncol. 2018. PMID: 29255239 Review.
Accelerating anticancer drug development - opportunities and trade-offs.
Nass SJ, Rothenberg ML, Pentz R, Hricak H, Abernethy A, Anderson K, Gee AW, Harvey RD, Piantadosi S, Bertagnolli MM, Schrag D, Schilsky RL. Nass SJ, et al. Among authors: schilsky rl. Nat Rev Clin Oncol. 2018 Dec;15(12):777-786. doi: 10.1038/s41571-018-0102-3. Nat Rev Clin Oncol. 2018. PMID: 30275514 Review.
Rationale and Design of the Targeted Agent and Profiling Utilization Registry (TAPUR) Study.
Mangat PK, Halabi S, Bruinooge SS, Garrett-Mayer E, Alva A, Janeway KA, Stella PJ, Voest E, Yost KJ, Perlmutter J, Pinto N, Kim ES, Schilsky RL. Mangat PK, et al. Among authors: schilsky rl. JCO Precis Oncol. 2018;2018:10.1200/PO.18.00122. doi: 10.1200/PO.18.00122. Epub 2018 Jul 11. JCO Precis Oncol. 2018. PMID: 30603737 Free PMC article.
Genomic and transcriptomic profiling expands precision cancer medicine: the WINTHER trial.
Rodon J, Soria JC, Berger R, Miller WH, Rubin E, Kugel A, Tsimberidou A, Saintigny P, Ackerstein A, Braña I, Loriot Y, Afshar M, Miller V, Wunder F, Bresson C, Martini JF, Raynaud J, Mendelsohn J, Batist G, Onn A, Tabernero J, Schilsky RL, Lazar V, Lee JJ, Kurzrock R. Rodon J, et al. Among authors: schilsky rl. Nat Med. 2019 May;25(5):751-758. doi: 10.1038/s41591-019-0424-4. Epub 2019 Apr 22. Nat Med. 2019. PMID: 31011205 Free PMC article. Clinical Trial.
An accelerated pathway for targeted cancer therapies.
McClellan M, Benner J, Schilsky R, Epstein D, Woosley R, Friend S, Sidransky D, Geoghegan C, Kessler D. McClellan M, et al. Nat Rev Drug Discov. 2011 Feb;10(2):79-80. doi: 10.1038/nrd3360. Nat Rev Drug Discov. 2011. PMID: 21283090
367 results