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The Drug Rediscovery protocol facilitates the expanded use of existing anticancer drugs.
van der Velden DL, Hoes LR, van der Wijngaart H, van Berge Henegouwen JM, van Werkhoven E, Roepman P, Schilsky RL, de Leng WWJ, Huitema ADR, Nuijen B, Nederlof PM, van Herpen CML, de Groot DJA, Devriese LA, Hoeben A, de Jonge MJA, Chalabi M, Smit EF, de Langen AJ, Mehra N, Labots M, Kapiteijn E, Sleijfer S, Cuppen E, Verheul HMW, Gelderblom H, Voest EE. van der Velden DL, et al. Among authors: kapiteijn e. Nature. 2019 Oct;574(7776):127-131. doi: 10.1038/s41586-019-1600-x. Epub 2019 Sep 30. Nature. 2019. PMID: 31570881 Clinical Trial.
New treatment modalities in advanced thyroid cancer.
Kapiteijn E, Schneider TC, Morreau H, Gelderblom H, Nortier JWR, Smit JWA. Kapiteijn E, et al. Ann Oncol. 2012 Jan;23(1):10-18. doi: 10.1093/annonc/mdr117. Epub 2011 Apr 6. Ann Oncol. 2012. PMID: 21471561 Free article. Review.
Serous Retinopathy Associated with Mitogen-Activated Protein Kinase Kinase Inhibition (Binimetinib) for Metastatic Cutaneous and Uveal Melanoma.
van Dijk EH, van Herpen CM, Marinkovic M, Haanen JB, Amundson D, Luyten GP, Jager MJ, Kapiteijn EH, Keunen JE, Adamus G, Boon CJ. van Dijk EH, et al. Among authors: kapiteijn eh. Ophthalmology. 2015 Sep;122(9):1907-16. doi: 10.1016/j.ophtha.2015.05.027. Epub 2015 Jun 26. Ophthalmology. 2015. PMID: 26123090 Clinical Trial.
Beneficial Effects of the mTOR Inhibitor Everolimus in Patients with Advanced Medullary Thyroid Carcinoma: Subgroup Results of a Phase II Trial.
Schneider TC, de Wit D, Links TP, van Erp NP, van der Hoeven JJ, Gelderblom H, van Wezel T, van Eijk R, Morreau H, Guchelaar HJ, Kapiteijn E. Schneider TC, et al. Among authors: kapiteijn e. Int J Endocrinol. 2015;2015:348124. doi: 10.1155/2015/348124. Epub 2015 Jul 29. Int J Endocrinol. 2015. PMID: 26294908 Free PMC article.
Everolimus pharmacokinetics and its exposure-toxicity relationship in patients with thyroid cancer.
de Wit D, Schneider TC, Moes DJ, Roozen CF, den Hartigh J, Gelderblom H, Guchelaar HJ, van der Hoeven JJ, Links TP, Kapiteijn E, van Erp NP. de Wit D, et al. Among authors: kapiteijn e. Cancer Chemother Pharmacol. 2016 Jul;78(1):63-71. doi: 10.1007/s00280-016-3050-6. Epub 2016 May 11. Cancer Chemother Pharmacol. 2016. PMID: 27169792 Free PMC article. Clinical Trial.
Treatment strategies and overall survival for incurable metastatic colorectal cancer - A EURECCA international comparison including 21,196 patients from the Netherlands and Norway.
Breugom AJ, Bastiaannet E, Guren MG, Kørner H, Boelens PG, Dekker FW, Kapiteijn E, Gelderblom H, Larsen IK, Liefers GJ, van de Velde CJH. Breugom AJ, et al. Among authors: kapiteijn e. Eur J Surg Oncol. 2020 Jun;46(6):1167-1173. doi: 10.1016/j.ejso.2020.02.005. Epub 2020 Feb 29. Eur J Surg Oncol. 2020. PMID: 32151531
Multi-omic analysis identifies hypoalbuminemia as independent biomarker of poor outcome upon PD-1 blockade in metastatic melanoma.
Leek LVM, Notohardjo JCL, de Joode K, Velker EL, Haanen JBAG, Suijkerbuijk KPM, Aarts MJB, de Groot JWB, Kapiteijn E, van den Berkmortel FWPJ, Westgeest HM, de Gruijl TD, Retel VP, Cuppen E, van der Veldt AAM, Labots M, Voest EE, van de Haar J, van den Eertwegh AJM. Leek LVM, et al. Among authors: kapiteijn e. Sci Rep. 2024 May 16;14(1):11244. doi: 10.1038/s41598-024-61150-y. Sci Rep. 2024. PMID: 38755213 Free PMC article.
Adjuvant chemotherapy for rectal cancer patients treated with preoperative (chemo)radiotherapy and total mesorectal excision: a Dutch Colorectal Cancer Group (DCCG) randomized phase III trial.
Breugom AJ, van Gijn W, Muller EW, Berglund Å, van den Broek CBM, Fokstuen T, Gelderblom H, Kapiteijn E, Leer JWH, Marijnen CAM, Martijn H, Meershoek-Klein Kranenbarg E, Nagtegaal ID, Påhlman L, Punt CJA, Putter H, Roodvoets AGH, Rutten HJT, Steup WH, Glimelius B, van de Velde CJH. Breugom AJ, et al. Among authors: kapiteijn e. Ann Oncol. 2015 Apr;26(4):696-701. doi: 10.1093/annonc/mdu560. Epub 2014 Dec 5. Ann Oncol. 2015. PMID: 25480874 Free article. Clinical Trial.
190 results