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New platelet aggregation inhibitors based on pyridazinone moiety.
Costas T, Costas-Lago MC, Vila N, Besada P, Cano E, Terán C. Costas T, et al. Among authors: cano e. Eur J Med Chem. 2015 Apr 13;94:113-22. doi: 10.1016/j.ejmech.2015.02.061. Epub 2015 Mar 3. Eur J Med Chem. 2015. PMID: 25757094
Pyridazines part 41: synthesis, antiplatelet activity and SAR of 2,4,6-substituted 5-(3-oxo-3-phenylprop-1-en-1-yl)- or 5-(3-phenylprop-2-enoyl)pyridazin-3(2H)-ones.
Crespo A, Meyers C, Coelho A, Yáñez M, Fraiz N, Sotelo E, Maes BU, Laguna R, Cano E, Lemière GL, Raviña E. Crespo A, et al. Among authors: cano e. Bioorg Med Chem Lett. 2006 Feb 15;16(4):1080-3. doi: 10.1016/j.bmcl.2005.10.073. Epub 2005 Nov 14. Bioorg Med Chem Lett. 2006. PMID: 16290144
249 results