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Unusual (+/-)-electrospray ionization induced fragmentation: Structural elucidation of an in-process synthetic intermediate of doravirine (MK-1439) using liquid chromatography/high-resolution tandem mass spectrometry and two-dimensional nuclear magnetic resonance.
Sheng H, Lexa KW, Zhang LK, Yang RS, Wright TJ, Sherry BD, Helmy R, Martin GE. Sheng H, et al. Among authors: yang rs. Rapid Commun Mass Spectrom. 2017 Apr 30;31(8):719-727. doi: 10.1002/rcm.7833. Rapid Commun Mass Spectrom. 2017. PMID: 28171682
Unexpected Propargylic Retro-Brook Rearrangements in Alkynes.
Wang X, Gao Q, Buevich AV, Yasuda N, Zhang Y, Yang RS, Zhang LK, Martin GE, Williamson RT. Wang X, et al. Among authors: yang rs. J Org Chem. 2019 Aug 16;84(16):10024-10031. doi: 10.1021/acs.joc.9b01190. Epub 2019 Jul 22. J Org Chem. 2019. PMID: 31283876
Engineering Hydroxylase Activity, Selectivity, and Stability for a Scalable Concise Synthesis of a Key Intermediate to Belzutifan.
Cheung-Lee WL, Kolev JN, McIntosh JA, Gil AA, Pan W, Xiao L, Velásquez JE, Gangam R, Winston MS, Li S, Abe K, Alwedi E, Dance ZEX, Fan H, Hiraga K, Kim J, Kosjek B, Le DN, Marzijarani NS, Mattern K, McMullen JP, Narsimhan K, Vikram A, Wang W, Yan JX, Yang RS, Zhang V, Zhong W, DiRocco DA, Morris WJ, Murphy GS, Maloney KM. Cheung-Lee WL, et al. Among authors: yang rs. Angew Chem Int Ed Engl. 2024 Mar 22;63(13):e202316133. doi: 10.1002/anie.202316133. Epub 2024 Feb 19. Angew Chem Int Ed Engl. 2024. PMID: 38279624
494 results