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Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma.
Bryant J, Batis N, Franke AC, Clancey G, Hartley M, Ryan G, Brooks J, Southam AD, Barnes N, Parish J, Roberts S, Khanim F, Spruce R, Mehanna H. Bryant J, et al. Among authors: parish j. Oncotarget. 2019 Aug 27;10(50):5229-5244. doi: 10.18632/oncotarget.27156. eCollection 2019 Aug 27. Oncotarget. 2019. PMID: 31497252 Free PMC article.
The anti-tumour activity of DNA methylation inhibitor 5-aza-2'-deoxycytidine is enhanced by the common analgesic paracetamol through induction of oxidative stress.
Gleneadie HJ, Baker AH, Batis N, Bryant J, Jiang Y, Clokie SJH, Mehanna H, Garcia P, Gendoo DMA, Roberts S, Burley M, Molinolo AA, Gutkind JS, Scheven BA, Cooper PR, Parish JL, Khanim FL, Wiench M. Gleneadie HJ, et al. Among authors: parish jl. Cancer Lett. 2021 Mar 31;501:172-186. doi: 10.1016/j.canlet.2020.12.029. Epub 2021 Jan 5. Cancer Lett. 2021. PMID: 33359448 Free PMC article.
Phase I trial of WEE1 inhibition with chemotherapy and radiotherapy as adjuvant treatment, and a window of opportunity trial with cisplatin in patients with head and neck cancer: the WISTERIA trial protocol.
Kong A, Good J, Kirkham A, Savage J, Mant R, Llewellyn L, Parish J, Spruce R, Forster M, Schipani S, Harrington K, Sacco J, Murray P, Middleton G, Yap C, Mehanna H. Kong A, et al. Among authors: parish j. BMJ Open. 2020 Mar 16;10(3):e033009. doi: 10.1136/bmjopen-2019-033009. BMJ Open. 2020. PMID: 32184305 Free PMC article. Clinical Trial.
Disruption of CTCF-YY1-dependent looping of the human papillomavirus genome activates differentiation-induced viral oncogene transcription.
Pentland I, Campos-León K, Cotic M, Davies KJ, Wood CD, Groves IJ, Burley M, Coleman N, Stockton JD, Noyvert B, Beggs AD, West MJ, Roberts S, Parish JL. Pentland I, et al. Among authors: parish jl. PLoS Biol. 2018 Oct 25;16(10):e2005752. doi: 10.1371/journal.pbio.2005752. eCollection 2018 Oct. PLoS Biol. 2018. PMID: 30359362 Free PMC article.
STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle.
Morgan EL, Wasson CW, Hanson L, Kealy D, Pentland I, McGuire V, Scarpini C, Coleman N, Arthur JSC, Parish JL, Roberts S, Macdonald A. Morgan EL, et al. Among authors: parish jl. PLoS Pathog. 2018 Apr 9;14(4):e1006975. doi: 10.1371/journal.ppat.1006975. eCollection 2018 Apr. PLoS Pathog. 2018. PMID: 29630659 Free PMC article.
303 results